LRCH1 and TMEM14A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LRCH1	TMEM14A
Description		leucine rich repeats and calponin homology domain containing 1	transmembrane protein 14A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of GTPase Activity Cellular Response To Chemokine Negative Regulation Of T Cell Migration	Mitochondrial Transport Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Immature fraction of reticulocytes ( 32888494) Ischemic stroke ( 29531354) Mean platelet volume ( 32888494 27863252) Mosquito bite size ( 28199695) Optic disc size ( 31809533) Platelet count ( 32888494) Platelet distribution width ( 32888494 27863252) PR interval ( 30679814 30046033 32439900) PR segment duration ( 24850809) Pulse pressure ( 30578418) QRS complex (12-leadsum) ( 27659466) Stroke ( 29531354) Systolic blood pressure ( 30224653)	Metabolite levels ( 23823483) Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Response to hepatitis B vaccine ( 29534301)
Interacting Genes		3 interacting genes: RB1 TMEM14A TMEM14B	35 interacting genes: AQP6 CLN8 CPLX4 CREB3 CREB3L1 CXCR3 ERBB3 ERBB4 ERGIC3 ERMAP IER3IP1 KCNK5 LMNA LRCH1 LXN MMGT1 MTNR1A MTNR1B MUC1 NEMP1 PDZK1IP1 SCN3B SERINC2 SLC10A6 SLC18A1 SLC19A3 SLC7A1 SSMEM1 TMEM14B TMEM179B TMEM31 TMEM51 TMEM80 TMEM86B USP18
Entrez ID		23143	28978
HPRD ID		14307	15522
Ensembl ID		ENSG00000136141	ENSG00000096092
Uniprot IDs		Q9Y2L9	Q9Y6G1
PDB IDs			2LOO 2LOP
Enriched GO Terms of Interacting Partners?
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