CLASP2 and CLIP2

Number of citations of the paper that reports this interaction (PubMedID 11290329)
190

Data Source:
HPRD (two hybrid, in vitro)

		CLASP2	CLIP2
Description		cytoplasmic linker associated protein 2	CAP-Gly domain containing linker protein 2
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GO Annotations	Cellular Component	Kinetochore Cytoplasm Golgi Apparatus Trans-Golgi Network Microtubule Organizing Center Kinetochore Microtubule Cytosol Microtubule Spindle Microtubule Cytoplasmic Microtubule Plasma Membrane Focal Adhesion Cell Cortex Membrane Cell Leading Edge Ruffle Membrane Basal Cortex Mitotic Spindle	Nucleus Cytoplasm Microtubule Associated Complex Microtubule Plus-end
	Molecular Function	Dystroglycan Binding Protein Binding Microtubule Binding Microtubule Plus-end Binding	Microtubule Binding Microtubule Plus-end Binding
	Biological Process	Microtubule Cytoskeleton Organization Vesicle Targeting Microtubule Nucleation Negative Regulation Of Microtubule Depolymerization Golgi Organization Mitotic Spindle Organization Establishment Or Maintenance Of Cell Polarity Exit From Mitosis Regulation Of Gastrulation Positive Regulation Of Epithelial Cell Migration Regulation Of Epithelial To Mesenchymal Transition Microtubule Organizing Center Organization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule-based Process Microtubule Anchoring Establishment Of Mitotic Spindle Localization Positive Regulation Of Exocytosis Cell Division Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Focal Adhesion Assembly Protein Localization To Plasma Membrane Positive Regulation Of Extracellular Matrix Disassembly Mitotic Spindle Assembly Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Positive Regulation Of Basement Membrane Assembly Involved In Embryonic Body Morphogenesis	Cytoplasmic Microtubule Organization
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Role of ABL in ROBO-SLIT signaling RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Age at suicide ( 31476763) Autism spectrum disorders (social interaction) ( 32624584) SAPHO syndrome ( 33816493)
Interacting Genes		16 interacting genes: ADRB2 AKT1 CCR4 CLIP1 CLIP2 CREBBP CSNK2A1 ERBB2 FEZ1 FEZ2 MAPRE1 MAPRE2 MARK3 PYGM RBFOX2 SRPK2	5 interacting genes: BMP1 CLASP2 DYNLL1 ITSN1 MAX
Entrez ID		23122	7461
HPRD ID		12054	09140
Ensembl ID		ENSG00000163539	ENSG00000106665
Uniprot IDs		E3W994 E7ERI8 O75122	A0A140VJG6 A7E2F7 Q9UDT6
PDB IDs		3WOY 5NR4	2CP2 2CP3
Enriched GO Terms of Interacting Partners?
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