TRIM35 and PAN2

Number of citations of the paper that reports this interaction (PubMedID 23105109)
19

Data Source:
BioGRID (two hybrid)

		TRIM35	PAN2
Description		tripartite motif containing 35	poly(A) specific ribonuclease subunit PAN2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	P-body Nucleus Cytosol PAN Complex
	Molecular Function	Molecular_function Zinc Ion Binding Ubiquitin Protein Ligase Activity	3'-5'-exoribonuclease Activity Nucleic Acid Binding Poly(A)-specific Ribonuclease Activity Thiol-dependent Deubiquitinase Protein Binding Metal Ion Binding
	Biological Process	Apoptotic Process Protein Ubiquitination Positive Regulation Of Apoptotic Process Innate Immune Response Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Viral Release From Host Cell	Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Processing Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways		Interferon gamma signaling	Deadenylation of mRNA
Drugs
Diseases
GWAS		Chronotype ( 30696823) Crohn's disease ( 26192919) Inflammatory bowel disease ( 26192919) Lung cancer ( 28604730)	Axial length ( 24144296) Height ( 34054925 25429064) Refractive error ( 32231278)
Interacting Genes		49 interacting genes: ADIPOQ BANP CABP2 COL8A1 DTX2 ENKD1 FNDC3B GNMT HNRNPA2B1 IGFN1 KANK2 LCK LMO1 MGAT5B NRF1 PAN2 PARD6B PDCD5 PHF24 PKM PPP2CA PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E QARS1 SHC3 SMARCB1 TCEANC TRAPPC6A TRIM10 TRIM11 TRIM5 TRIM55 TRIM63 TSG101 TSSK3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2K UBE2U UBE2W USP2 USP49 ZNF410	9 interacting genes: ATM DYNLL1 PABPC1 PAN3 RBBP8 RBCK1 RNF144B TNRC6A TRIM35
Entrez ID		23087	9924
HPRD ID		15553	15640
Ensembl ID		ENSG00000104228	ENSG00000135473
Uniprot IDs		E5RGB3 Q9UPQ4	Q504Q3
PDB IDs
Enriched GO Terms of Interacting Partners?
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