UNC13A and EPB41L3

Number of citations of the paper that reports this interaction (PubMedID 12421765)
41

Data Source:
BioGRID (two hybrid)

		UNC13A	EPB41L3
Description		unc-13 homolog A	erythrocyte membrane protein band 4.1 like 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Synaptic Vesicle Membrane Neuromuscular Junction Presynaptic Membrane Neuron Projection Terminal Bouton Presynaptic Active Zone Presynaptic Active Zone Cytoplasmic Component	Cytosol Cytoskeleton Plasma Membrane Cell-cell Junction Cell Junction Axolemma Paranode Region Of Axon Juxtaparanode Region Of Axon
	Molecular Function	Calcium Ion Binding Calmodulin Binding Phospholipid Binding Syntaxin-1 Binding Diacylglycerol Binding	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Protein-membrane Anchor Activity
	Biological Process	Neurotransmitter Secretion Neuromuscular Junction Development Synaptic Vesicle Docking Synaptic Vesicle Priming Synaptic Vesicle Maturation Cell Differentiation Synaptic Transmission, Glutamatergic Intracellular Signal Transduction Regulation Of Synaptic Transmission, Glutamatergic Dense Core Granule Priming Neuronal Dense Core Vesicle Exocytosis Presynaptic Dense Core Vesicle Exocytosis Positive Regulation Of Dendrite Extension	Regulation Of Cell Growth Protein Localization To Paranode Region Of Axon Apoptotic Process Biological_process Regulation Of Cell Shape Cortical Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Paranodal Junction Assembly Actomyosin Structure Organization Myelin Maintenance Neuron Projection Morphogenesis Protein Localization To Juxtaparanode Region Of Axon Protein Localization To Plasma Membrane
Pathways			Neurexins and neuroligins Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis ( 29566793 22959728 27455348 19734901 24931836) Amyotrophic lateral sclerosis (sporadic) ( 24256812 28931804) Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals ( 22959728) Benign prostatic hyperplasia ( 30988330) Frontotemporal dementia ( 24931836) IgG levels ( 28628107) Obesity-related traits ( 23251661)	Cerebral amyloid deposition (PET imaging) ( 26252872) Chronic kidney disease ( 31152163) Diverticular disease ( 30177863) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Glomerular filtration rate (creatinine) ( 28452372) Lacunar stroke ( 33773637) Optic nerve head parameters (multi-trait analysis) ( 31798171) Sleep duration ( 25469926) Social communication problems ( 24564958) Thyroid nodules ( 30099483) Vertical cup-disc ratio ( 31798171)
Interacting Genes		2 interacting genes: EPB41L3 UBXN10	20 interacting genes: ATXN1L CADM1 CEP152 CLNS1A CNTNAP2 HSPB1 IGSF21 MBIP PAXIP1 PSEN1 SPANXN2 SPTBN1 TCF4 TYMS UNC13A YWHAB YWHAG YWHAH YWHAQ YWHAZ
Entrez ID		23025	23136
HPRD ID		19058	05622
Ensembl ID		ENSG00000130477	ENSG00000082397
Uniprot IDs		Q9UPW8	A0A0A0MRA8 A8K968 Q9Y2J2
PDB IDs			2HE7 3BIN 5RYM 5RYN 5RYO 5RYP 5RYQ 5RYR 5RYS 5RYT 5RYU 5RYV 5RYW 5RYX 5RYY 5RYZ 5RZ0 5RZ1 5RZ2 5RZ3 5RZ4 5RZ5 5RZ6 5RZ7 5RZ8 5RZ9 5RZA 5RZB 5RZC 5RZD 5RZE 5RZF 5RZG 5RZH 5RZI 5RZJ 5RZK 5RZL 5RZM 5RZN 5RZO 5RZP 5RZQ 5RZR 5RZS 5RZT 5RZU 5RZV 5RZW 5RZX 5RZY 5RZZ 5S00 6IBE
Enriched GO Terms of Interacting Partners?
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