PALLD and HOMER2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PALLD	HOMER2
Description		palladin, cytoskeletal associated protein	homer scaffold protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Stress Fiber Ruffle Podosome Nucleus Cytosol Actin Filament Plasma Membrane Focal Adhesion Actin Cytoskeleton Z Disc Lamellipodium Axon Growth Cone Excitatory Synapse	Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Dendrite Stereocilium Tip Neuronal Cell Body Intracellular Organelle Apical Part Of Cell Glutamatergic Synapse
	Molecular Function	Actin Binding Protein Binding Muscle Alpha-actinin Binding Cell-cell Adhesion Mediator Activity	Actin Binding Protein Binding Protein Domain Specific Binding Synaptic Receptor Adaptor Activity G Protein-coupled Glutamate Receptor Binding Identical Protein Binding Protein-containing Complex Binding
	Biological Process	Keratinocyte Development Epithelial Cell Morphogenesis Cytoskeleton Organization Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Cell Migration Actin Cytoskeleton Organization Dendrite Self-avoidance	G Protein-coupled Glutamate Receptor Signaling Pathway Sensory Perception Of Sound Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Interleukin-2 Production Calcium-mediated Signaling Using Intracellular Calcium Source Behavioral Response To Cocaine Chemical Homeostasis Within A Tissue Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Store-operated Calcium Entry
Pathways			Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Advanced glycation end-product levels ( 26915486) Bacteremia ( 27236921) Coronary artery disease ( 29212778 33020668) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Non-alcoholic fatty liver disease histology (AST) ( 20708005) Pulse pressure ( 28135244 27841878 30578418) Response to iloperidone treatment (QT prolongation) ( 18521091) Systolic blood pressure ( 30578418) Vein graft stenosis in coronary artery bypass grafting ( 25881214)	Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Tourette syndrome ( 30818990)
Interacting Genes		12 interacting genes: ACTN1 ACTN2 CDC42 EZR HOMER2 HOMER3 ITGB5 LIG4 PDLIM3 SORBS2 SRPK2 SUMO2	15 interacting genes: ABI3 AGAP2 APP DBN1 FXR1 GRM1 ITPR1 KPNA2 LZTS2 PALLD PJA1 RYR1 SMURF1 UBXN1 VKORC1
Entrez ID		23022	9455
HPRD ID		09731	07269
Ensembl ID		ENSG00000129116	ENSG00000103942
Uniprot IDs		B2RTX2 Q8WX93	Q9NSB8
PDB IDs		2DM2 2DM3
Enriched GO Terms of Interacting Partners?
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