TRIM32 and RAB29

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TRIM32	RAB29
Description		tripartite motif containing 32	RAB29, member RAS oncogene family
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Striated Muscle Myosin Thick Filament	Cytoplasm Mitochondrion Early Endosome Vacuole Golgi Apparatus Cis-Golgi Network Trans-Golgi Network Cytosol Cytoskeleton Plasma Membrane Endomembrane System Melanosome Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Exosome Intracellular Vesicle
	Molecular Function	Transcription Coactivator Activity RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Myosin Binding Tat Protein Binding Translation Initiation Factor Binding Identical Protein Binding Ubiquitin Binding Protein Self-association Ubiquitin Protein Ligase Activity	GTPase Activity Protein Binding GTP Binding GDP Binding Kinesin Binding Small GTPase Binding Dynein Complex Binding
	Biological Process	Protein Polyubiquitination Tissue Homeostasis Ubiquitin-dependent Protein Catabolic Process Actin Ubiquitination Response To UV Protein Ubiquitination Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Negative Regulation Of Viral Transcription Response To Tumor Necrosis Factor Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Fat Cell Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Protein Catabolic Process Positive Regulation Of Cell Cycle Positive Regulation Of Proteolysis Positive Regulation Of Transcription, DNA-templated Muscle Cell Cellular Homeostasis Negative Regulation Of Fibroblast Proliferation Positive Regulation Of Neurogenesis Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Striated Muscle Cell Differentiation Axon Development Protein K48-linked Ubiquitination Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Interleukin-17-mediated Signaling Pathway Positive Regulation Of Chemokine (C-C Motif) Ligand 20 Production Positive Regulation Of Cell Motility	Positive Regulation Of Receptor Recycling Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Mitochondrion Organization Golgi Organization Synapse Assembly Response To Bacterium Negative Regulation Of Neuron Projection Development Cell Differentiation Melanosome Organization Viral RNA Genome Replication T Cell Activation Retrograde Transport, Endosome To Golgi Positive Regulation Of T Cell Receptor Signaling Pathway Protein Localization To Membrane Positive Regulation Of Intracellular Protein Transport Regulation Of Neuron Death Toxin Transport Protein Localization To Ciliary Membrane Regulation Of Retrograde Transport, Endosome To Golgi
Pathways		Regulation of innate immune responses to cytosolic DNA Antigen processing: Ubiquitination & Proteasome degradation	RAB geranylgeranylation
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462) Hip circumference adjusted for BMI ( 34021172)	Liver enzyme levels (alkaline phosphatase) ( 33972514) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		70 interacting genes: ABI2 AKTIP APOL1 ASIC4 ASTN2 ATP2B1 ATXN1 CLIP4 DERL1 ERGIC3 FADS6 GABARAP GABARAPL1 GABARAPL2 GEM GLIS2 GPR137B GSN HSPA4 ICMT IQCB1 IRAK1 KCTD9 LCN2 MAP1LC3A MAP1LC3B MAP1LC3C MID2 MOB1A MYCN NDRG2 NPAS3 NTAQ1 PDE9A PELI2 PIAS3 PIAS4 POLE3 PTCD2 PTPN11 RAB29 RABAC1 RNF208 RNF41 SCGB1A1 SDCBP STING1 SYT6 TCEANC TNC TOP1 TRIM23 TRIM27 TRIM5 TRIM72 TTC23 UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBE2V1 UBQLN1 UBQLN4 VPS11 XIAP	8 interacting genes: BEND7 C11orf49 LDOC1 LRRK1 LSM7 REL TRIM27 TRIM32
Entrez ID		22954	8934
HPRD ID		03797	11962
Ensembl ID		ENSG00000119401	ENSG00000117280
Uniprot IDs		A0A024R843 Q13049	B2R7I9 O14966 Q6FGU7
PDB IDs		2CT2 5FEY	6HH2
Enriched GO Terms of Interacting Partners?
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