RPIA and ATPAF2

Number of citations of the paper that reports this interaction (PubMedID 25910212)
170

Data Source:
BioGRID (two hybrid, two hybrid)

		RPIA	ATPAF2
Description		ribose 5-phosphate isomerase A	ATP synthase mitochondrial F1 complex assembly factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intracellular Membrane-bounded Organelle	Mitochondrion Cytosol Nuclear Speck
	Molecular Function	Ribose-5-phosphate Isomerase Activity Protein Binding Identical Protein Binding Monosaccharide Binding	Protein Binding
	Biological Process	D-ribose Metabolic Process Pentose-phosphate Shunt Pentose-phosphate Shunt, Non-oxidative Branch Ribose Phosphate Metabolic Process	Mitochondrial Proton-transporting ATP Synthase Complex Assembly Proton-transporting ATP Synthase Complex Assembly
Pathways		RPIA deficiency: failed conversion of R5P to RU5P RPIA deficiency: failed conversion of RU5P to R5P Pentose phosphate pathway
Drugs		4-phospho-L-threonic acid
Diseases
GWAS		Blood protein levels ( 30072576)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Schizophrenia ( 28991256 25056061 29483656) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		21 interacting genes: ATPAF2 C14orf119 CENPP DDIT4L FOXP2 FXR1 FXR2 GORASP2 HSPB8 LNX1 NIF3L1 NTAQ1 PCDH7 PCMT1 PICK1 PTPN11 RNF208 SDCBP STK16 TXN2 VTA1	74 interacting genes: AKAP8L APP ATP5F1A ATP5F1B BEGAIN C11orf1 CDC14A CDK2AP1 CEP57 CFAP206 CRTC2 CTIF CYSRT1 DDIT3 DLGAP4 EBF1 EBF3 EIF4G1 EWSR1 FAM166B FCHSD2 FNTB GOLGA6L9 IKZF3 INCA1 KRT34 KRT40 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP6-2 KRTAP6-3 LGALS9B LNX1 LRRFIP2 LURAP1L LZTS2 MAGEA6 MEDAG MIF4GD NME4 PAK5 PKP4 POLR2J3 POLR3F POLR3H PPP1R16B PPP1R32 PRDM14 PRDM6 RAD54B RBM48 RCN1 REL RPH3AL RPIA SORBS2 SPATC1L SPG21 TCHP TERT TFIP11 TP53BP2 TRIM23 TRIM27 UBAP2 VWC2 WASHC1 ZFP90 ZNF19 ZNF23 ZNF35 ZNF426 ZNF655
Entrez ID		22934	91647
HPRD ID		01589	10599
Ensembl ID		ENSG00000153574	ENSG00000171953
Uniprot IDs		P49247	Q8N5M1
PDB IDs
Enriched GO Terms of Interacting Partners?
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