ZBTB1 and AKR7A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZBTB1	AKR7A2
Description		zinc finger and BTB domain containing 1	aldo-keto reductase family 7 member A2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Centrosome Nuclear Body Nuclear Membrane	Cytoplasm Golgi Apparatus Cytosol Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity K63-linked Polyubiquitin Modification-dependent Protein Binding	Alditol:NADP+ 1-oxidoreductase Activity Aldo-keto Reductase (NADP) Activity Protein Binding Electron Transfer Activity Phenanthrene-9,10-epoxide Hydrolase Activity D-threo-aldose 1-dehydrogenase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of T Cell Mediated Immunity DNA Repair Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Translesion Synthesis Cell Differentiation Positive Regulation Of Natural Killer Cell Differentiation Cellular Response To UV MRNA Transcription By RNA Polymerase II Innate Immune Response Positive Regulation Of T Cell Differentiation Thymus Development Protein Homooligomerization Positive Regulation Of Pro-T Cell Differentiation	Carbohydrate Metabolic Process Cellular Aldehyde Metabolic Process Electron Transport Chain Daunorubicin Metabolic Process Doxorubicin Metabolic Process
Pathways			Aflatoxin activation and detoxification
Drugs
Diseases
GWAS		Lymphocyte counts ( 32888494) Neutrophil percentage of white cells ( 32888494) Urinary albumin-to-creatinine ratio ( 31630189)	Blood protein levels ( 30072576) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Pre-treatment viral load in HIV-1 infection ( 31219150) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
Interacting Genes		22 interacting genes: AKR7A2 AR EWSR1 FAM161A FANCG HEMGN KAT5 LZTR1 MAML3 MFAP1 NDN PCNA PIH1D2 PIM1 SCNM1 TRAF1 TRIM42 UBC UBE2I ZBTB25 ZNF417 ZNF572	6 interacting genes: AKR7A3 EMC1 F2 MCPH1 TRIM63 ZBTB1
Entrez ID		22890	8574
HPRD ID		15688	04567
Ensembl ID		ENSG00000126804	ENSG00000053371
Uniprot IDs		Q9Y2K1	B4DZX4 O43488 V9HWA2
PDB IDs			2BP1
Enriched GO Terms of Interacting Partners?
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