CLSTN1 and APBB1

Number of citations of the paper that reports this interaction (PubMedID 17332754)
63

Data Source:
HPRD (in vivo)

		CLSTN1	APBB1
Description		calsyntenin 1	amyloid beta precursor protein binding family B member 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Nucleus Endoplasmic Reticulum Membrane Cell Surface Postsynaptic Membrane Postsynaptic Endosome Glutamatergic Synapse GABA-ergic Synapse Integral Component Of Postsynaptic Density Membrane Integral Component Of Spine Apparatus Membrane	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Plasma Membrane Nuclear Speck Lamellipodium Growth Cone Protein-containing Complex Presynaptic Membrane Neuronal Cell Body Dendritic Spine Main Axon Synapse Postsynaptic Membrane Perinuclear Region Of Cytoplasm Growth Cone Lamellipodium Growth Cone Filopodium
	Molecular Function	Amyloid-beta Binding Calcium Ion Binding Protein Binding Kinesin Binding X11-like Protein Binding	Amyloid-beta Binding Chromatin Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding Ubiquitin Protein Ligase Binding Histone Binding Protein-containing Complex Binding Tau Protein Binding Low-density Lipoprotein Particle Receptor Binding Proline-rich Region Binding DNA-binding Transcription Factor Binding
	Biological Process	Regulation Of Cell Growth Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Positive Regulation Of Synaptic Transmission Positive Regulation Of Synapse Assembly Regulation Of Synapse Maturation Neurotransmitter Receptor Transport To Postsynaptic Membrane Vesicle-mediated Transport In Synapse	Negative Regulation Of Transcription By RNA Polymerase II Double-strand Break Repair Regulation Of Transcription, DNA-templated Apoptotic Process Smooth Muscle Contraction Cellular Response To DNA Damage Stimulus Signal Transduction Axonogenesis Response To Iron Ion Positive Regulation Of Neuron Projection Development Positive Regulation Of Apoptotic Process Histone H4 Acetylation Positive Regulation Of DNA Repair Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Secretion Negative Regulation Of Cell Cycle G1/S Phase Transition
Pathways			Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Drugs
Diseases
GWAS			Blood protein levels ( 29875488) Malaria ( 31844061)
Interacting Genes		14 interacting genes: APBA2 APBB1 BAHCC1 COL17A1 KIF2A KLC1 KLC2 MCM3AP MDM2 PRNP SETDB1 SLK TOPBP1 TRIP12	69 interacting genes: ABI1 ABL1 ANXA1 APLP1 APLP2 APP ATXN1 ATXN1L CCDC97 CHERP CLSTN1 CPSF6 CPSF7 CYFIP1 CYFIP2 DDX17 DDX3X DDX46 DHX15 DHX9 DIAPH1 DIAPH2 EGFR ELMO1 ENAH ERBB2 EVL FASLG HNRNPH1 HNRNPK HTATSF1 KAT5 KHDRBS1 KHSRP LRP1 LRP2 NONO PABPC1 PQBP1 PRKAR2A PRNP PTBP1 RBM17 RPL4 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ TENM1 TFCP2 THRAP3 TSHZ1 TSHZ2 TSHZ3 U2AF2 VASP WAS WASF2 WASL WBP11 WIPF1 WIPF2 YBX1 YLPM1
Entrez ID		22883	322
HPRD ID		10837	04087
Ensembl ID		ENSG00000171603	ENSG00000166313
Uniprot IDs		B4E3Q1 O94985	B7Z4M9 O00213
PDB IDs			2E45 2HO2 2IDH 2OEI 3D8D 3D8E 3D8F 3DXC 3DXD 3DXE 5NQH
Enriched GO Terms of Interacting Partners?
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