ZHX2 and DHRS2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ZHX2	DHRS2
Description		zinc fingers and homeoboxes 2	dehydrogenase/reductase 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity	Carbonyl Reductase (NADPH) Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II MRNA Catabolic Process Somatic Stem Cell Population Maintenance Negative Regulation Of Neuron Differentiation Negative Regulation Of Transcription, DNA-templated Retinal Bipolar Neuron Differentiation	C21-steroid Hormone Metabolic Process Negative Regulation Of Cell Population Proliferation Response To Toxic Substance Electron Transport Chain Cellular Response To Oxidative Stress Myeloid Dendritic Cell Differentiation Negative Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Carotid intima media thickness ( 30510157 21909108) Chin dimples ( 27182965) Immune response to smallpox vaccine (IL-6) ( 22542470) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Reticulocyte count ( 32888494)
Interacting Genes		10 interacting genes: APP ATXN1 DHRS2 LAT NAGPA NFYA RAB7A YWHAQ ZHX1 ZHX3	5 interacting genes: APPBP2 EXOSC5 FBXO7 TCEA2 ZHX2
Entrez ID		22882	10202
HPRD ID		16458	07483
Ensembl ID		ENSG00000178764	ENSG00000100867
Uniprot IDs		Q9Y6X8	Q13268
PDB IDs		2DMP 3NAU
Enriched GO Terms of Interacting Partners?
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