R3HDM2 and SPRY3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		R3HDM2	SPRY3
Description		R3H domain containing 2	sprouty RTK signaling antagonist 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytosol Membrane
	Molecular Function	RNA Binding Protein Binding	Molecular_function Protein Binding
	Biological Process		Multicellular Organism Development Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of MAP Kinase Activity Negative Regulation Of MAPK Cascade Negative Regulation Of Ras Protein Signal Transduction Animal Organ Development Axon Development Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Neuron Projection Arborization
Pathways
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 29875488) Blood urea nitrogen levels ( 31152163) Body mass index ( 28552196) Body size at age 10 ( 32376654) Chronotype ( 30696823) Coronary artery disease ( 33020668) Estimated glomerular filtration rate ( 31152163 31015462) Glomerular filtration rate (creatinine) ( 28452372) HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Low density lipoprotein cholesterol levels ( 32154731) Monocyte count ( 32888494) Red blood cell count ( 32888494) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Triglyceride levels ( 32203549 32154731) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglycerides ( 30275531) Urate levels ( 20884846 31578528) Urate levels in overweight individuals ( 25811787)	Idiopathic osteonecrosis of the femoral head ( 28000841) Iron status biomarkers (transferrin saturation) ( 28334935)
Interacting Genes		26 interacting genes: ADAMTSL4 ATXN1 C1orf94 CYSRT1 FAM168A INCA1 KRT31 KRT34 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP12-3 KRTAP13-3 KRTAP3-2 KRTAP4-12 MEI4 MGAT5B NBPF19 NOTCH2NLA RBPMS REL SPRY1 SPRY3 TRIM42	27 interacting genes: AQP1 BEX2 CATSPER1 CHRD CREB5 GNE GPSM3 HOXA1 HR KPRP KRT34 LCE1A LCE1B LCE1F LCE2B LCE3A LCE3D LCE3E MAPKBP1 MEOX2 NEK6 R3HDM2 SLC39A7 VSNL1 ZDHHC17 ZNF587 ZNF655
Entrez ID		22864	10251
HPRD ID		13827	03917
Ensembl ID		ENSG00000179912	ENSG00000168939
Uniprot IDs		A0A0U1RRA6 B5MCG9 Q9Y2K5	O43610 Q6ZUP3
PDB IDs		1WHR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?