PUF60 and H1-2

Number of citations of the paper that reports this interaction (PubMedID 18258596)
53

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		PUF60	H1-2
Description		poly(U) binding splicing factor 60	H1.2 linker histone, cluster member
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cell Junction	Nucleosome Euchromatin Nucleus Transcriptionally Active Chromatin
	Molecular Function	DNA Binding RNA Binding Protein Binding Identical Protein Binding Cadherin Binding	Double-stranded DNA Binding RNA Binding Protein Binding Chromatin DNA Binding Nucleosomal DNA Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splice Site Selection Apoptotic Process	Negative Regulation Of Transcription By RNA Polymerase II Nucleosome Assembly Nucleosome Positioning Chromosome Condensation Negative Regulation Of DNA Recombination Histone H3-K4 Trimethylation Histone H3-K27 Trimethylation
Pathways		mRNA Splicing - Major Pathway	Apoptosis induced DNA fragmentation Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS
Interacting Genes		104 interacting genes: ARL8A BORCS5 CACNA1A CCNC CD101 CHD3 CPEB2 DDIT4L ERG FBXO7 FHL2 FTHL17 FUBP1 H1-2 ID3 IQCN KHDC4 LARP7 MED28 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR9-1 MIR9-3 MIR92A1 MIR92A2 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F2 MIRLET7G MIRLET7I MYCBP2 OGT PCBP1 PCBP3 PPP1R16A PTBP2 QRICH1 RAD23B RAP1GDS1 SAP30BP SDCBP SF1 SIAH1 SNRPF SRSF11 TAF2 TH U2AF2 UBE2I UBTFL1 UPF2 VIM YWHAG ZG16	29 interacting genes: AEBP2 APP ASXL1 CDC73 CSNK2A2 CTNNB1 CTR9 CUL4A DDB1 F10 HELLS IL7R IRAK4 KPNA7 KPNB1 LEO1 NASP NCL NSD1 PAF1 PARP1 POLR2A PRKCA PRKDC PUF60 SNCA VHL WDR12 YBX1
Entrez ID		22827	3006
HPRD ID		18051	07514
Ensembl ID		ENSG00000179950	ENSG00000187837
Uniprot IDs		Q9UHX1	P16403
PDB IDs		2DNY 2KXF 2KXH 2QFJ 3DXB 3UE2 3US5 3UWT 5KVY 5KW1 5KW6 5KWQ 6LUR 6SLO
Enriched GO Terms of Interacting Partners?
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