CASC3 and MIR128-1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		CASC3	MIR128-1
Description		CASC3 exon junction complex subunit	microRNA 128-1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Cytoplasmic Stress Granule Nuclear Speck Dendrite Nuclear Membrane Exon-exon Junction Complex Perinuclear Region Of Cytoplasm U2-type Catalytic Step 1 Spliceosome	Extracellular Space
	Molecular Function	RNA Binding MRNA Binding Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding Identical Protein Binding	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Splicing, Via Spliceosome Regulation Of Translation Intracellular MRNA Localization MRNA Transport	Positive Regulation Of Protein Phosphorylation Negative Regulation Of Gene Expression Negative Regulation Of Lipoprotein Particle Clearance Negative Regulation Of Cell Migration Negative Regulation Of Transporter Activity Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Cholesterol Homeostasis Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Cell Adhesion Lipid Homeostasis Cellular Response To Lipopolysaccharide Negative Regulation Of Cholesterol Efflux Negative Regulation Of Lipoprotein Transport Positive Regulation Of Neuroinflammatory Response Negative Regulation Of Macrophage Colony-stimulating Factor Production Positive Regulation Of Microglial Cell Activation Negative Regulation Of Macrophage Migration
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Asthma ( 31619474) Household income ( 31844048)	Body mass index ( 26426971)
Interacting Genes		18 interacting genes: AKT1 APC CASP8 CDK6 CDKN2A EIF4A3 ESR2 FGFR4 GRB2 KRTAP6-2 MIR128-1 NBN PHB PTPN1 PTPRJ STARD3 STAU1 TSC1	91 interacting genes: AIMP1 AIMP2 APOBEC3B ATXN2 ATXN2L C1QBP CASC3 CELF1 CPSF6 CRTAP DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 FAM98A FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC LSM10 LSM11 MARS1 MATR3 MSI2 NOL6 NONO NUDT16L1 NUFIP2 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PUF60 PURA PURB QARS1 RARS1 RBFOX2 RBM10 RBM12B RBM14 RBM17 RBM4 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SYNCRIP TAF15 TENT2 TRA2A TRA2B U2SURP UPF1 USP36 UTP20 YBX1 YBX2 YBX3 ZFR
Entrez ID		22794	406915
HPRD ID		16225
Ensembl ID		ENSG00000108349	ENSG00000207654
Uniprot IDs		O15234
PDB IDs		2HYI 2J0Q 2J0S 2J0U 2XB2 3EX7 5XJC 5YZG 6ICZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?