Description |
fibroblast growth factor receptor 4 |
mitogen-activated protein kinase kinase 5 |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Activated partial thromboplastin time ( 22703881)
- Apolipoprotein A1 levels ( 32203549)
- Body fat distribution (arm fat ratio) ( 30664634)
- Body fat distribution (trunk fat ratio) ( 30664634)
- Body shape index ( 34021172)
- Circulating fibroblast growth factor 23 levels ( 30217807)
- Height ( 28552196 25282103 31562340)
- Hemoglobin levels ( 32327693)
- Hip circumference adjusted for BMI ( 34021172)
- Hip index ( 34021172)
- Hip shape (DXA scan) ( 30320955)
- Narrowest width of the femoral neck ( 30888730)
- Nonsyndromic cleft lip ( 31609978)
- Type 2 diabetes ( 32499647 30718926)
- Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
- Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist circumference adjusted for BMI in active individuals ( 28448500)
- Waist circumference adjusted for BMI in non-smokers ( 28443625)
- Waist circumference adjusted for BMI in smokers ( 28443625)
- Waist circumference adjusted for body mass index ( 34021172 25673412 28448500)
- Waist-hip index ( 34021172)
- Waist-to-hip ratio adjusted for BMI ( 34021172 26426971)
- Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
- Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
- Waist-to-hip ratio adjusted for body mass index ( 26785701 25673412)
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Interacting Genes |
85 interacting genes:
ABCB5
AKT1
ANGPTL4
ARAF
ARNT
BECN1
BLID
CASC3
CBLC
CCND2
CCNE1
CD44
CDH2
CDK4
CDK6
CDKN2A
CDKN2B
CDKN2C
DIRAS3
EPHA2
EPHA4
EPSTI1
ERBB2
ERRFI1
FGF1
FGF17
FGF18
FGF19
FGF2
FGF3
FGF4
FGF5
FGF6
FGF7
FGF8
FGF9
FZR1
GLCE
GLIS2
GRM1
HGF
HIF1A
IFT80
IGF1R
KDELR2
LATS2
LRATD2
MAP2K5
MAP2K6
MAP3K5
MAPK14
MDM4
MET
MSH2
MTA3
MYC
NF2
NSD3
OSGIN1
PDGFRA
PDLIM2
PLCG1
PPP3CA
PSMC3IP
PTPN11
PTPN12
PTPN6
PTPRR
RAF1
RASL10B
RASSF1
RNF20
ROS1
SCGB3A1
STAT1
STAT3
STC2
STK11
TEAD2
TERT
THRSP
TP53
TSC1
TTYH2
WIF1
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57 interacting genes:
AKT1
ARAF
ARNT
ASRGL1
BAD
BBS2
BECN1
C3orf36
CCND2
CD44
CDC42BPB
CDK4
CDK6
CDKN2A
CDKN2B
CDKN2C
DUSP21
EPHA2
ERBB2
ESRRA
FGFR4
FZR1
GLIS2
GRM1
GUCD1
HGF
HIF1A
LATS2
LNX2
MAP2K3
MAP2K6
MAP3K2
MAP3K3
MAPK7
MDM4
MET
MYC
NF2
NMB
PARD6A
PDGFRA
PFDN5
PRKCI
PRKCZ
RAF1
RPL28
SQSTM1
STAMBP
STK11
TEAD2
TERT
TP53
TSC1
XRCC6
YWHAZ
ZNF426
ZNF620
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Entrez ID |
2264 |
5607 |
HPRD ID |
00625 |
03951 |
Ensembl ID |
ENSG00000160867
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ENSG00000137764
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Uniprot IDs |
B4DVP5
J3KPQ0
P22455
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A0A024R5X5
A0A024R5Y2
Q13163
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PDB IDs |
1QCT
4QQ5
4QQC
4QQJ
4QQT
4QRC
4R6V
4TYE
4TYG
4TYI
4TYJ
4UXQ
4XCU
5JKG
5NUD
5NWZ
5XFF
5XFJ
6IUO
6IUP
6J6Y
6JPE
6JPJ
6NVG
6NVH
6NVI
6NVJ
6NVK
6V9C
6YI8
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2NPT
2O2V
4IC7
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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