ALDOA and ENO3

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		ALDOA	ENO3
Description		aldolase, fructose-bisphosphate A	enolase 3
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytosol Actin Cytoskeleton Membrane Platelet Alpha Granule Lumen M Band I Band Secretory Granule Lumen Sperm Head Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Phosphopyruvate Hydratase Complex Extracellular Space Cytosol Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	RNA Binding Actin Binding Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding Tubulin Binding Identical Protein Binding Cadherin Binding Fructose Binding	Magnesium Ion Binding Phosphopyruvate Hydratase Activity Identical Protein Binding Protein-containing Complex Binding
	Biological Process	Fructose Metabolic Process Glycolytic Process ATP Biosynthetic Process Striated Muscle Contraction Actin Filament Organization Binding Of Sperm To Zona Pellucida Regulation Of Cell Shape Fructose 1,6-bisphosphate Metabolic Process Muscle Cell Cellular Homeostasis Protein Homotetramerization	Glycolytic Process Aging Response To Xenobiotic Stimulus Skeletal Muscle Tissue Regeneration
Pathways		Platelet degranulation Neutrophil degranulation Glycolysis Gluconeogenesis	Glycolysis Gluconeogenesis
Drugs		Zinc 1,6-Fructose Diphosphate (Linear Form) Dihydroxyacetone phosphate 1,6-DI-O-PHOSPHONO-D-MANNITOL N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form	2-phospho-D-glyceric acid Phosphoenolpyruvate 2-Phosphoglycolic Acid Phosphonoacetohydroxamic Acid
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Cataracts ( 34127677) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Monocyte count ( 32888494) Plateletcrit ( 32888494) Schizophrenia ( 25056061 29483656)	Keratoconus ( 33649486) Red cell distribution width ( 32888494)
Interacting Genes		35 interacting genes: ADRB2 ALDOB ATP6V1E1 BCAT2 CACNA1A CYTH2 DYNLL1 EGFR ENO1 ENO3 ERBB2 ERBB3 ERBB4 FANCA GALNT6 GPD2 HSD17B10 HSPB2 IFNA4 LINC01554 MLH1 MYOC OGT PCNA PIAS4 PLD2 SHANK3 SLC22A1 SRPK2 SUMO4 TERF1 TGM2 TRIM63 TUBB XRN1	20 interacting genes: ALDOA APP DCTN1 DSP HSPB2 KALRN LINC01554 MAN2A2 MTMR14 NEB PGM1 PKM PNKD SGCG SNAPIN SPTB TCAP TRAPPC2 TRIM63 TTN
Entrez ID		226	2027
HPRD ID		00070	11746
Ensembl ID		ENSG00000149925	ENSG00000108515
Uniprot IDs		P04075 V9HWN7	P13929
PDB IDs		1ALD 2ALD 4ALD 5KY6	2XSX
Enriched GO Terms of Interacting Partners?
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