FGF12 and RNF151

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FGF12	RNF151
Description		fibroblast growth factor 12	ring finger protein 151
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Synapse	Nucleus Cytoplasm
	Molecular Function	Protein Binding Growth Factor Activity Sodium Channel Regulator Activity Transmembrane Transporter Binding	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Membrane Depolarization Signal Transduction Cell-cell Signaling Chemical Synaptic Transmission Nervous System Development Heart Development Adult Locomotory Behavior Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Sodium Ion Transport Neuromuscular Process Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Neuronal Action Potential Regulation Of Sodium Ion Transmembrane Transport Regulation Of Voltage-gated Sodium Channel Activity Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Cation Channel Activity	Spermatogenesis Protein Ubiquitination Cell Differentiation
Pathways		Phase 0 - rapid depolarisation
Drugs
Diseases
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Bipolar disorder ( 31043756) Fasting glucose ( 34059833) Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821) HDL cholesterol levels in HIV infection ( 33109212) Height ( 32902719) Hip circumference adjusted for BMI ( 28552196) Idiopathic dilated cardiomyopathy ( 29495422) Ileal carcinoids ( 21139019) Major depressive disorder ( 23377640) Metabolite levels ( 19043545) Orofacial cleft x maternal periconceptional smoking interaction (1df) ( 33937227) Post bronchodilator FEV1/FVC ratio ( 26634245) PR interval ( 32439900) Serum metabolite concentrations in chronic kidney disease ( 29545352) Severe influenza A (H1N1) infection ( 26379185) Sleep quality ( 23728906)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		27 interacting genes: AP2M1 APP COIL CT45A1 DACH1 DCTD DPPA2 GRIP1 IKZF1 IL2RA LZTS2 MAPK13 MAPK8IP2 NEDD4 NEDD4L PJA1 RBAK RNF151 RP9 SMURF1 SRPK1 SRPK2 STAC3 THAP1 YWHAE ZNF460 ZNF79	18 interacting genes: ABT1 APP C1orf35 CT45A1 DVL3 FAM133A FAM9A FGF12 NKAPD1 PIBF1 PRPF3 SCARA5 SREK1IP1 TSPYL2 UBC UBE2D2 UBE2I ZC4H2
Entrez ID		2257	146310
HPRD ID		03303	19116
Ensembl ID		ENSG00000114279	ENSG00000179580
Uniprot IDs		P61328	H3BNJ8 Q2KHN1
PDB IDs		1Q1U 4JQ0
Enriched GO Terms of Interacting Partners?
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