FDXR and FDX1

Number of citations of the paper that reports this interaction (PubMedID 1917982)
27

Data Source:
HPRD (in vitro)

		FDXR	FDX1
Description		ferredoxin reductase	ferredoxin 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix	Mitochondrion Mitochondrial Matrix
	Molecular Function	Ferredoxin-NADP+ Reductase Activity NADPH-adrenodoxin Reductase Activity Oxidoreductase Activity	Iron Ion Binding Electron Transfer Activity 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Steroid Biosynthetic Process Ubiquinone Biosynthetic Process Cholesterol Metabolic Process	Steroid Biosynthetic Process Cholesterol Metabolic Process Electron Transport Chain Hormone Biosynthetic Process Cellular Response To CAMP Cellular Response To Forskolin
Pathways		Pregnenolone biosynthesis Endogenous sterols Electron transport from NADPH to Ferredoxin Defective CYP11A1 causes AICSR	Mitochondrial iron-sulfur cluster biogenesis Pregnenolone biosynthesis Endogenous sterols Electron transport from NADPH to Ferredoxin Defective CYP11A1 causes AICSR
Drugs		Flavin adenine dinucleotide Nicotinamide adenine dinucleotide phosphate	Mitotane
Diseases
GWAS			Cognitive function ( 24684796) Coronary artery disease ( 32469254) Serum metabolite levels ( 33031748)
Interacting Genes		5 interacting genes: FDX1 FHIT MTNR1A OGT POU2F1	12 interacting genes: BIRC2 BIRC3 CNTN5 CORO2A CYCS CYP11A1 CYP11B2 FDXR LILRB2 PBRM1 PRKAB2 RDH5
Entrez ID		2232	2230
HPRD ID		00060	00059
Ensembl ID		ENSG00000161513	ENSG00000137714
Uniprot IDs		A0A0A0MSZ4 A0A0A0MT64 A0A0A0MTN9 A0A0A0MTR6 A0A0C4DFN8 A0A0C4DGN7 P22570	P10109
PDB IDs			3N9Y 3N9Z 3NA0 3NA1 3P1M
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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