FOXK1 and ASXL1

Number of citations of the paper that reports this interaction (PubMedID 27705803)
84

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid)

		FOXK1	ASXL1
Description		forkhead box K1	ASXL transcriptional regulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm	Nucleoplasm PR-DUB Complex
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding 14-3-3 Protein Binding Sequence-specific Double-stranded DNA Binding	DNA Binding Chromatin Binding Transcription Coactivator Activity Protein Binding Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cellular Glucose Homeostasis Regulation Of Transcription By RNA Polymerase II Muscle Organ Development Negative Regulation Of Autophagy Regulation Of Glucose Metabolic Process Cell Differentiation Response To Starvation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Canonical Glycolysis	Cell Morphogenesis Heart Morphogenesis Animal Organ Morphogenesis Negative Regulation Of Lipid Storage Hemopoiesis Response To Retinoic Acid Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Monoubiquitinated Histone H2A Deubiquitination Regulation Of Kidney Size Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Thymus Development Bone Marrow Development Homeostasis Of Number Of Cells Lung Saccule Development Glomerular Visceral Epithelial Cell Development
Pathways		UCH proteinases	UCH proteinases
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Cognitive decline rate in late mild cognitive impairment ( 26252872) Diastolic blood pressure ( 30224653) Disease progression in age-related macular degeneration ( 29346644) Emotional lability in attention deficit hyperactivity disorder ( 31085060) Heel bone mineral density ( 30598549) Itch intensity from mosquito bite ( 28199695) Mosquito bite size ( 28199695)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Inflammatory bowel disease ( 28067908) Red cell distribution width ( 32888494)
Interacting Genes		4 interacting genes: ASXL1 IRF2 PTEN SRF	17 interacting genes: APP DEFB115 DEFB116 FASN FOXK1 FOXK2 GOLGA6L9 H1-2 ID1 IRAG1 MRPS7 NCOA6 POLD1 SRM SRPK1 STAT3 UBC
Entrez ID		221937	171023
HPRD ID		18750	16516
Ensembl ID		ENSG00000164916	ENSG00000171456
Uniprot IDs		P85037	Q498B9 Q8IXJ9
PDB IDs
Enriched GO Terms of Interacting Partners?
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