FGD2 and KLHL12

  • Number of citations of the paper that reports this interaction (PubMedID 25416956)
  • 484
  • Data Source:
  • BioGRID (two hybrid)

FGD2

KLHL12

Description FYVE, RhoGEF and PH domain containing 2 kelch like family member 12
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acne (severe) ( 24927181)
  • Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678)
  • Medication use (thyroid preparations) ( 31015401)
  • Monocyte count ( 32888494)
  • Rosacea symptom severity ( 29771307)
Interacting Genes 5 interacting genes: CDC42 KLHL12 PLEKHG4 RPRM TMEM239 62 interacting genes: ARAF ARRDC1 ATXN1 BAG6 BCL6 C1QTNF2 CARD10 CCBE1 COL8A1 CPSF6 CRTC3 CUL3 DGCR6 DRD4 DVL2 DVL3 FAM90A1 FBXL17 FGD2 FLNA GLYCTK INMT KEAP1 KHSRP KLHL2 KLHL24 KLHL3 LNPK LNX1 MAPRE1 MED25 MED28 MPP1 MRPL10 MTNR1A MYO15B NDC80 NTAQ1 PDGFRB PEA15 PEF1 PLEKHA4 PNKP PRR13 RGL3 RIN1 RIT1 RNF4 RPP25L SDCBP SEC31A SNX20 SYNE4 TAOK2 TBC1D10C TCEANC TTBK2 UBE2I VEGFB VTA1 ZBP1 ZBTB4
Entrez ID 221472 59349
HPRD ID 05478 13925
Ensembl ID ENSG00000146192 ENSG00000117153
Uniprot IDs Q7Z6J4 Q53G59 Q9H7R2
PDB IDs 2VPJ 6TTK 6V7O
Enriched GO Terms of Interacting Partners?
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