SKA1 and CCDC196

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SKA1	CCDC196
Description		spindle and kinetochore associated complex subunit 1	coiled-coil domain containing 196
Image			No pdb structure
GO Annotations	Cellular Component	Outer Kinetochore Cytosol Spindle Microtubule Microtubule Cytoskeleton Mitotic Spindle
	Molecular Function	Protein Binding Microtubule Binding
	Biological Process	Mitotic Cell Cycle Chromosome Segregation Regulation Of Microtubule Polymerization Or Depolymerization Cell Division
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Itch intensity from mosquito bite adjusted by bite size ( 28199695) Large HDL particle concentration ( 29084231) Phospholipid levels in large HDL ( 29084231) Phospholipid levels in medium HDL ( 29084231)	Cirrhosis (alcohol related) ( 32853455)
Interacting Genes		12 interacting genes: AURKB BLOC1S6 CCDC196 CCDC197 FAM9C NDC80 PSMC5 SKA2 SNAPIN SPC24 SSC5D SYCE1	32 interacting genes: AMOTL2 ANKRD11 BORCS5 DTNB EIF3F HGS IFT74 KRT20 KRT28 KRT31 KRT34 KRT35 KRT37 KRT39 MEIS2 MEOX2 NXF1 PIK3R3 PKNOX2 RAB3IP SKA1 SNAPC5 STX11 SYCE1L SYCE2 TFIP11 TXLNA TXLNB UBL5 USHBP1 WASF1 ZGPAT
Entrez ID		220134	440184
HPRD ID		12689	14708
Ensembl ID		ENSG00000154839	ENSG00000196553
Uniprot IDs		A0A024R294 Q96BD8
PDB IDs		4AJ5 4C9Y 4CA0
Enriched GO Terms of Interacting Partners?
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