CBY2 and GRAP2

Number of citations of the paper that reports this interaction (PubMedID 27107012)
40

Data Source:
BioGRID (two hybrid)

		CBY2	GRAP2
Description		chibby family member 2	GRB2 related adaptor protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasmic Vesicle	Nucleus Nucleoplasm Cytoplasm Endosome Cytosol Plasma Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Ras Protein Signal Transduction Cell-cell Signaling
Pathways			Signaling by SCF-KIT Generation of second messenger molecules DAP12 signaling FCERI mediated MAPK activation FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization CD28 co-stimulation FLT3 Signaling
Drugs
Diseases
GWAS			Body mass index ( 26426971) Systemic lupus erythematosus ( 28714469)
Interacting Genes		119 interacting genes: ACTN1 AIMP2 ARHGEF40 ARMC7 BEX3 C19orf44 C1orf109 CCDC146 CCDC185 CCDC187 CCDC198 CCDC57 CCHCR1 CCNG1 CDC23 CDC37 CDK18 CDK2 CEP44 CEP55 CEP57L1 CEP95 CHCHD3 CHIC2 CIBAR1 CKS1B CNNM3 CYTH4 DGCR6 DTNB DUSP14 DZIP1L EFCAB3 EIF4E2 ELOA ENKD1 FAM161A FANCG FARS2 FBXO17 FRS3 GADD45A GADD45GIP1 GOLGA2 GOLGA6A GOLGA6L2 GRAP2 HAUS1 HSF2BP ING5 ISCU KIAA0408 KIFC3 KLC3 LATS1 LENG1 LMO1 LMO2 LMO3 LNX1 MCRS1 MED28 METTL17 MLH1 MMAB MOS NDUFA5 NEK6 NINL NME7 NTAQ1 OIP5 PID1 PIN1 PLEKHN1 POLR1C PPFIA3 PPP1R13B PPP1R18 PRPF18 PRPF31 RCOR3 RNF6 RPL9 RTP5 RUNX1T1 SCNM1 SDCBP SH3RF2 SNAPC5 SSX3 SYCE1 SYT17 TCEA2 TCEANC TCHP TEX11 TRIM42 TRIML2 TSC2 TSGA10 TSGA10IP TUBGCP4 TXK TXLNA TXLNB USHBP1 ZC2HC1C ZFYVE26 ZMAT2 ZNF250 ZNF417 ZNF564 ZNF572 ZNF581 ZNF655 ZNF688 ZNF764 ZNF785	81 interacting genes: AR BAG4 BEND5 BLNK CBL CBLB CBY2 CCHCR1 CCNDBP1 CD28 COG6 CSF1R DNM2 DVL2 EGFR ERBB2 ERBB3 ERBB4 ETV5 FASLG GAB1 GAB2 GAB3 GAREM1 GATA1 GFAP GOLGA2 GRB2 HNRNPK IHO1 IKZF3 KHDRBS1 KHDRBS2 KIT KPRP KRT13 KRTAP1-3 KRTAP4-11 KRTAP4-12 LAT LATS2 LAX1 LCP2 LNX1 LNX2 MAGED1 MAP4K1 MKRN3 MOS MTUS2 PBLD PNMA1 PRKAA2 PRPH2 PRR35 RACK1 RAVER1 RBPMS RBX1 RIN3 RINT1 SH2D4A SHB SHC1 SLC25A17 SOS2 SPRY2 SSX2IP STAMBP TFIP11 TLE5 TRAF1 TSNAXIP1 USP8 WWP2 YWHAE ZBTB7B ZNF250 ZNF319 ZNF526 ZSCAN21
Entrez ID		220082	9402
HPRD ID		14856	05156
Ensembl ID		ENSG00000174015	ENSG00000100351
Uniprot IDs		A0A140VJV5 Q8NA61	B7Z8E3 O75791 Q6FI14
PDB IDs			5GJH
Enriched GO Terms of Interacting Partners?
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