ACSL4 and HTATIP2

Number of citations of the paper that reports this interaction (PubMedID 21252234)
30

Data Source:
BioGRID (pull down)

		ACSL4	HTATIP2
Description		acyl-CoA synthetase long chain family member 4	HIV-1 Tat interactive protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrial Outer Membrane Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Plasma Membrane Membrane Integral Component Of Membrane Neuronal Cell Body Mitochondria-associated Endoplasmic Reticulum Membrane Extracellular Exosome	Nucleus Nuclear Envelope Cytoplasm Cytosol Membrane
	Molecular Function	Long-chain Fatty Acid-CoA Ligase Activity ATP Binding Very Long-chain Fatty Acid-CoA Ligase Activity Arachidonate-CoA Ligase Activity Palmitoyl-CoA Ligase Activity	Transcription Coactivator Activity Protein Serine/threonine Kinase Activity Protein Binding Oxidoreductase Activity
	Biological Process	Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Response To Nutrient Fatty Acid Transport Triglyceride Biosynthetic Process Neuron Differentiation Positive Regulation Of Insulin Secretion Long-chain Fatty-acyl-CoA Metabolic Process Long-chain Fatty-acyl-CoA Biosynthetic Process Embryonic Process Involved In Female Pregnancy Dendritic Spine Development Response To Interleukin-15	Angiogenesis Regulation Of Transcription By RNA Polymerase II Apoptotic Process Cell Differentiation Negative Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Angiogenesis Positive Regulation Of Transcription By RNA Polymerase II Protein Autophosphorylation Import Into Nucleus
Pathways		Intracellular metabolism of fatty acids regulates insulin secretion Synthesis of very long-chain fatty acyl-CoAs
Drugs		Icosapent Troglitazone Rosiglitazone	Polyethylene glycol 400
Diseases
GWAS		Mean platelet volume ( 32888494)	Bell's palsy ( 33602968) Fractional shortening ( 29403010) Obesity-related traits ( 23251661) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762)
Interacting Genes		4 interacting genes: APP DSE HTATIP2 YWHAQ	25 interacting genes: ABHD4 ACSL4 AQP6 ASF1A EHHADH ETS1 FAM209A FITM2 GET1 HDAC6 HSD17B11 JAGN1 JPH1 MIEF1 MTIF3 NCOA5 PITPNC1 PLIN2 RAB5A REEP4 RETREG3 SH3GLB1 SLC10A6 TMEM115 TMX2
Entrez ID		2182	10553
HPRD ID		02152	09288
Ensembl ID		ENSG00000068366	ENSG00000109854
Uniprot IDs		O60488 Q8TAF6	Q9BUP3
PDB IDs			2BKA
Enriched GO Terms of Interacting Partners?
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