ALDH3A1 and FKBP6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ALDH3A1	FKBP6
Description		aldehyde dehydrogenase 3 family member A1	FKBP prolyl isomerase family member 6 (inactive)
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GO Annotations	Cellular Component	Extracellular Space Cytoplasm Endoplasmic Reticulum Cytosol Plasma Membrane Integral Component Of Membrane	Synaptonemal Complex Cytoplasm Cytosol
	Molecular Function	Aldehyde Dehydrogenase (NAD+) Activity Aldehyde Dehydrogenase [NAD(P)+] Activity Protein Binding Alcohol Dehydrogenase (NADP+) Activity Benzaldehyde Dehydrogenase (NAD+) Activity	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding Identical Protein Binding Hsp90 Protein Binding
	Biological Process	Response To Hypoxia Cellular Aldehyde Metabolic Process Xenobiotic Metabolic Process Aging Response To Nutrient Positive Regulation Of Cell Population Proliferation Response To Xenobiotic Stimulus Response To Glucocorticoid Response To CAMP	Protein Folding Spermatogenesis Cell Differentiation Gene Silencing By RNA PiRNA Metabolic Process DNA Methylation Involved In Gamete Generation Positive Regulation Of Viral Genome Replication Meiotic Cell Cycle
Pathways		Phase I - Functionalization of compounds	Meiotic synapsis PIWI-interacting RNA (piRNA) biogenesis
Drugs		NADH
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Blood protein levels ( 30072576 29875488) Intraocular pressure ( 29617998) Keratoconus ( 33649486) Refractive astigmatism ( 30306274)	Height ( 31562340) Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
Interacting Genes		5 interacting genes: CYHR1 FBXL12 FKBP6 POT1 SRF	37 interacting genes: ACD ALDH3A1 CCDC198 CCNK CDK5RAP3 CFP CRACR2A DDIT4L DLGAP4 ECM1 EEF1D ENKD1 FAM107A GAPDH GSC2 HSP90AA1 IHO1 KANK2 KRT75 LZTS2 MAP3K1 MEI4 MEOX2 NME7 NTAQ1 PIAS2 PICK1 PPP1R32 RAB11FIP2 RNF4 SUMO1P1 TEPSIN TINF2 TMEM9B TRIM55 TRIM63 ZNF655
Entrez ID		218	8468
HPRD ID		00004	05326
Ensembl ID		ENSG00000108602	ENSG00000077800
Uniprot IDs		I3L3I9 P30838 Q6PKA6	A0A3B3IST2 O75344
PDB IDs		3SZA 3SZB 4H80 4L1O 4L2O	3B7X
Enriched GO Terms of Interacting Partners?
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