F2RL2 and F11R

Number of citations of the paper that reports this interaction (PubMedID 17057644)
43

Data Source:
HPRD (in vitro)

		F2RL2	F11R
Description		coagulation factor II thrombin receptor like 2	F11 receptor
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane Protein-containing Complex	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Integral Component Of Membrane Cell Junction Cytoplasmic Vesicle Protein-containing Complex Slit Diaphragm Extracellular Exosome Tight Junction
	Molecular Function	Phosphatidylinositol Phospholipase C Activity G Protein-coupled Receptor Activity Protein Binding Thrombin-activated Receptor Activity	Virus Receptor Activity Integrin Binding Protein Binding PDZ Domain Binding Protein Homodimerization Activity Cadherin Binding
	Biological Process	Blood Coagulation Response To Wounding Platelet Activation Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Thrombin-activated Receptor Signaling Pathway	Regulation Of Cytokine Production Inflammatory Response Leukocyte Cell-cell Adhesion Regulation Of Cell Shape Response To Radiation Actomyosin Structure Organization Regulation Of Actin Cytoskeleton Organization Negative Regulation Of GTPase Activity Positive Regulation Of Rho Protein Signal Transduction Maintenance Of Blood-brain Barrier Memory T Cell Extravasation Positive Regulation Of GTPase Activity Positive Regulation Of Blood Pressure Viral Entry Into Host Cell Intestinal Absorption Regulation Of Cytoskeleton Organization Negative Regulation Of Stress Fiber Assembly Cellular Response To Mechanical Stimulus Protein Localization To Plasma Membrane Establishment Of Endothelial Intestinal Barrier Regulation Of Membrane Permeability Cell-cell Adhesion Positive Regulation Of Platelet Aggregation Protein Localization To Bicellular Tight Junction Positive Regulation Of Establishment Of Endothelial Barrier Regulation Of Actin Cytoskeleton Reorganization Regulation Of Bicellular Tight Junction Assembly
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs)	Cell surface interactions at the vascular wall Integrin cell surface interactions TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) Tight junction interactions
Drugs
Diseases
GWAS		Mean platelet volume ( 28031487) Phenylephrine infusion rate during anesthesia ( 31455332)	Inflammatory bowel disease ( 23128233) Night sleep phenotypes ( 27126917)
Interacting Genes		9 interacting genes: AMT CDH5 CTSG ECT2 F11R F2 F2RL3 JAM2 JAM3	31 interacting genes: AFDN ASIP BDNF CAMLG CASK CGN CSNK2A1 EVL F2RL2 ITGAL JAGN1 MARCHF2 MMP14 MPDZ MYADM PARD3 PEX19 PGAP2 PICK1 PRKCA PTPRB RABAC1 SGTA SLC30A2 SLC35A1 SNAP47 STRIT1 TJP1 TMEM100 TMEM147 TMEM86B
Entrez ID		2151	50848
HPRD ID		03561	12038
Ensembl ID		ENSG00000164220	ENSG00000158769
Uniprot IDs		O00254	Q6FIB4 Q9Y624
PDB IDs			1NBQ 3EOY 3TSZ 4ODB
Enriched GO Terms of Interacting Partners?
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