Description |
estrogen receptor 1 |
phosphatase and tensin homolog |
Image |
|
|
GO Annotations |
Cellular Component |
|
|
Molecular Function |
|
|
Biological Process |
|
|
Pathways |
|
|
Drugs |
- Diethylstilbestrol
- Chlorotrianisene
- Conjugated estrogens
- Desogestrel
- Levonorgestrel
- Progesterone
- Lindane
- Raloxifene
- Toremifene
- Medroxyprogesterone acetate
- Testosterone
- Mitotane
- Estrone
- Tamoxifen
- Hexachlorophene
- Estradiol
- Ethynodiol diacetate
- Dobutamine
- Clomifene
- Dienestrol
- Fulvestrant
- Norgestimate
- Ethinylestradiol
- Melatonin
- Trilostane
- Naloxone
- Fluoxymesterone
- Estramustine
- Mestranol
- Danazol
- Oxybenzone
- Allylestrenol
- Zinc
- Genistein
- Prasterone
- Benzophenone
- Equilin
- Compound 19
- Resveratrol
- Compound 18
- Phthalic Acid
- Pyrazole
- Stanolone
- Naringenin
- Compound 4-D
- 1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol
- Quercetin
- Afimoxifene
- 2-Phenyl-1-[4-(2-Piperidin-1-Yl-Ethoxy)-Phenyl]-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol
- Estriol
- Estrone sulfate
- Quinestrol
- Phenolphthalein
- Permethrin
- Ospemifene
- AP1081
- Custirsen
- NP-50301
- CHF 4227
- TAS-108
- Lasofoxifene
- Arzoxifene
- Elacestrant
- Bazedoxifene
- Methyltestosterone
- beta-Naphthoflavone
- 17-METHYL-17-ALPHA-DIHYDROEQUILENIN
- 4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol
- [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE
- 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- 4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- (2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL
- (3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL
- (9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL
- (9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL
- 3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
- 3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
- Hexestrol
- dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate
- Erteberel
- N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]-2-(2-PHENYL-1H-INDOL-3-YL)ACETAMIDE
- (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL
- 4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol
- 4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL
- DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE
- 2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
- 4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL
- 2-(4-hydroxyphenyl)benzo[b]thiophen-6-ol
- Tibolone
- Eugenol
- Synthetic Conjugated Estrogens, A
- Synthetic Conjugated Estrogens, B
- Polyestradiol phosphate
- Norethynodrel
- Octocrylene
- Homosalate
- Enzacamene
- Zeranol
- Ractopamine
- Gestrinone
- Propyl Gallate
- 2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol
- Testosterone cypionate
- Testosterone enanthate
- Testosterone undecanoate
- Stanolone acetate
- Estradiol acetate
- Estradiol benzoate
- Estradiol cypionate
- Estradiol dienanthate
- Estradiol valerate
- Zinc acetate
- Zinc chloride
- Zinc sulfate, unspecified form
- Estriol tripropionate
- Fluoroestradiol F-18
|
|
Diseases |
|
|
GWAS |
|
|
Interacting Genes |
372 interacting genes:
ACTN4
AHR
AKAP13
AKT1
AKT2
ALYREF
ANGPTL4
ANP32B
AR
ARHGEF15
ARID1A
ARNT
ATAD2
BAG1
BAP1
BARD1
BCAR1
BCAS2
BDNF
BRCA1
CALM1
CALM2
CALM3
CAV1
CBLL1
CCND1
CCNH
CCNT1
CCT2
CDC25B
CDK2
CDK7
CDK8
CDKN1A
CEBPA
CEBPB
CFL1
CHD9
CHUK
CITED1
COPS5
CREBBP
CSNK2B
CSRP1
CTNNB1
CUEDC2
CUL4B
CXCL1
DAP3
DARS1
DBN1
DDX1
DDX17
DDX3X
DDX43
DDX5
DDX54
DHX9
DNMT3L
DNTTIP2
DUT
EEF2
EGFR
EHMT2
EIF2S2
EIF3I
EIF4A3
EP300
EPAS1
EPRS1
EPSTI1
ERBB2
ESR2
ESRRA
FARSA
FBH1
FHL2
FKBP4
FKBP5
FLII
FNDC1
FOXK2
FOXO1
FOXO3
FOXO4
FUBP1
GADD45B
GADD45G
GLCE
GNAI1
GRB2
GRIP1
GRWD1
GTF2B
GTF2H1
H2AC20
H2BC10
H2BC4
H2BC5
H2BC6
H2BC7
H2BC8
H3-3A
H3-3B
HBP1
HDAC3
HDAC4
HDAC5
HDAC9
HDLBP
HEXIM1
HNF4A
HNRNPA1
HNRNPA2B1
HNRNPC
HNRNPD
HSP90AA1
HSP90AB1
HSP90B1
HSPA4
HSPA8
HSPB1
IGF1R
ILF3
ING1
ISL1
ITGB3BP
JUN
JUNB
JUND
KARS1
KAT5
KATNA1
KDM5A
KIF1A
KLF5
KLK5
KLK9
KMT2D
KMT5B
KRT10
KRT18
KRT19
KRT8
LARS1
LCK
LCOR
LDB1
LINC00312
LRIF1
MAPK1
MAPK14
MAPK3
MARS1
MDM2
MED1
MED10
MED12
MED13
MED14
MED16
MED17
MED20
MED21
MED23
MED24
MED27
MED6
MED7
MEN1
MGMT
MKNK2
MMS19
MNAT1
MPG
MSH2
MTA1
MTA2
MTCH2
MTHFD1
MTOR
MUC1
MVP
MYBBP1A
MYH6
NAP1L4
NCL
NCOA1
NCOA2
NCOA3
NCOA4
NCOA6
NCOA7
NCOR1
NCOR2
NELFB
NFKB1
NONO
NPM1
NPPA
NR0B1
NR0B2
NR1H4
NR2C1
NR2C2
NR2F1
NR2F6
NRIP1
NSD1
NSD2
NSD3
NSF
NUDT21
OTUB1
P4HB
PA2G4
PAGR1
PAK1
PAK6
PBXIP1
PDIA3
PELP1
PGC
PGR
PHB
PHB2
PIAS1
PIAS2
PIAS3
PIK3R1
PIK3R3
PNRC2
POLR1B
POLR2A
POLR2D
POU2F1
POU2F2
POU4F1
POU4F2
PPARGC1A
PPARGC1B
PPIB
PPID
PPP1CA
PPP2R1A
PQBP1
PRDM2
PRKACA
PRKCSH
PRMT1
PRMT2
PRPF19
PRPF6
PSMC3IP
PSMC5
PSMD1
PSPC1
PTEN
PTGES3
PTMA
PTPN1
PTPN6
RAC3
RACK1
RANBP9
RARA
RBBP4
RBBP7
RBFOX2
RBM23
RBM39
RELA
REXO4
RFX4
RGS3
RLIM
RNF14
RNF4
RPL27A
RPL9
RPS6KA1
RPS6KA3
RTCB
RXRA
SAFB
SAFB2
SARNP
SARS2
SEPTIN2
SEPTIN8
SERBP1
SERPINB5
SET
SETD7
SFPQ
SHC1
SHMT2
SKIL
SKP2
SLC30A9
SMAD2
SMAD3
SMAD4
SMARCA2
SMARCA4
SMARCD1
SMARCD3
SMARCE1
SMC1A
SMC3
SMYD2
SND1
SNX6
SOS1
SP1
SP3
SPDEF
SRA1
SRC
SREBF1
STAT3
STAT5A
STRN
STUB1
SUV39H1
SVIL
SYNCRIP
TADA3
TAF10
TAF1A
TAF1B
TAF2
TAP1
TBP
TCERG1
TCF20
TDG
THRA
THRB
TNFRSF14
TOPBP1
TP53
TRAM1
TRIM24
TRIM25
TRIM28
TRIM59
TRIM8
TRIP4
TRRAP
TSC2
TUBA1B
TUBA1C
TUBB
TXNRD1
UBE2I
UBE3A
UBE4B
UIMC1
USF1
UST
VAV3
VCP
WBP2
WIPI1
XBP1
YARS1
YWHAH
YWHAQ
ZBTB16
ZBTB17
ZNF398
|
377 interacting genes:
AATK
ABCF2
ACTL6A
ADAR
AFP
AKAP12
AKT1
AKT3
ALYREF
AMOT
ANAPC10
ANAPC7
ANG
ANP32B
ANP32E
ANXA2
AR
ARF4
ARL3
ARMCX3
ASCC3
ATP5F1A
ATP5F1C
BCAR1
BEX1
BUB3
CACTIN-AS1
CAD
CALM1
CAMK2G
CAV1
CCDC180
CCDC47
CCND2
CCT2
CCT3
CCT4
CCT6A
CCT8
CDC27
CEP170
CEP97
CFL1
CHD4
CHGB
CMAS
COL18A1
COPA
COPB1
COPS6
CREB1
CSNK1A1
CSNK2A1
CSNK2A2
CUL4B
CXCL1
CXXC1
DAP3
DAXX
DBN1
DCAF11
DCAF13
DDB1
DDOST
DDX1
DDX21
DDX24
DDX47
DDX50
DHX15
DHX9
DLC1
DLG1
DNAJA1
DNAJA2
DNAJA3
DNAJB6
DNAJC10
DPM1
DRG1
DSP
EEF2
EIF4E
EIF6
EML1
EPHA2
EPRS1
ERBB3
ESR1
EXOSC1
EXOSC2
EXOSC4
EXOSC5
EXOSC7
FARSA
FARSB
FASN
FBL
FBXW11
FGF7
FLNA
FOXK1
FUBP3
GEMIN4
GNAI1
GNAI2
GNB4
GNL3
GPC4
GSTM2
GTF3C2
GTF3C3
GTF3C5
H2AC4
H2AX
HADHA
HBA1
HNRNPA1
HNRNPA3
HNRNPAB
HNRNPUL1
HSD17B1
HSD17B10
HSP90AB1
HSP90B1
HSPA4
HSPA4L
HSPA8
HSPBP1
HSPD1
HSPH1
IL24
ILF2
ILF3
INS
IPO5
IPO7
IRS4
ITPRID2
JUP
KBTBD4
KDM1A
KIF20B
KPNB1
LATS1
LGALS1
LIMA1
LINC00839
LINC01198
LINC02023
LIPF
LMNB1
LRPPRC
LTV1
MAGED2
MAGI2
MAGI3
MAP2K3
MAST1
MAST2
MAST3
MATR3
MCM2
MCM3
MCM5
MCRS1
MDC1
MDN1
METTL26
MEX3C
MKI67
MME
MPRIP
MRPS22
MRPS23
MRPS27
MRPS28
MRPS7
MRPS9
MSH6
MTHFD2
MVP
MYBBP1A
MYC
MYH10
MYL12A
MYO1B
MYO1C
MYO1D
MYOF
NACA
NCBP1
NCF1
NCSTN
NDFIP1
NEDD4
NGB
NOP56
NOP58
NPM3
NR3C1
NUMB
OSGIN1
OTUD3
PBK
PBRM1
PCNA
PDGFRB
PELO
PELP1
PHB
PHB2
PICK1
PKM
PLEC
PLK1
POLDIP2
POLR1A
POLR2A
POLR2B
POLR2H
POP1
PPL
PPP1CA
PPP2CA
PRDX1
PRDX3
PRKDC
PRPF19
PRPF8
PSMD3
PSMD4
PSMD7
PTDSS1
PTK2
PTK7
PURA
PXN
QPCTL
RAD21
RANBP2
RANGAP1
RBBP5
RBM15B
RBM4
RCC2
RCN1
RFC3
RFC4
RFC5
RING1
RPL10
RPL10A
RPL12
RPL13
RPL13A
RPL14
RPL17
RPL18A
RPL21
RPL22
RPL22L1
RPL23
RPL23A
RPL27
RPL27A
RPL28
RPL30
RPL31
RPL32
RPL34
RPL36
RPL38
RPL7
RPLP0
RPLP2
RPN2
RPP30
RPP38
RPP40
RPS11
RPS13
RPS15
RPS15A
RPS17
RPS2
RPS20
RPS23
RPS25
RPS26
RPS27
RPS27A
RPS3
RPS4X
RPS5
RPS6
RPS9
RSL1D1
RYBP
S100A8
S100A9
SDC1
SDC4
SDCBP
SEC61A1
SET
SETX
SIN3A
SIRT4
SKP1
SLC25A1
SLC25A13
SLC25A3
SLC25A5
SLC9A3R1
SLC9A3R2
SMARCA4
SMARCA5
SMC2
SMC4
SMCHD1
SMURF1
SNAI1
SNRNP200
SNRPA1
SNRPB2
SNRPD1
SNTB2
SNX27
SPTAN1
SPTBN1
SRP14
SSB
SSR4
SSRP1
STAG2
STK11
STRAP
STUB1
SUDS3
SUGP2
TCF25
TCP1
TECR
TERF2IP
THOC2
THOC3
THOC6
TMEFF1
TNKS
TNKS2
TP53
TP53BP1
TRIM28
TRMO
TUBA1B
TUBB
TUBB4B
TUFM
TWIST1
TXN
U2AF1
UBE2I
UBE2L3
UPF1
USP7
USP9X
UTP14A
UTRN
XRCC5
XRCC6
YAF2
YAP1
YES1
YTHDC2
YTHDF2
ZNF326
|
Entrez ID |
2099 |
5728 |
HPRD ID |
00589 |
03431 |
Ensembl ID |
ENSG00000091831
|
ENSG00000171862
|
Uniprot IDs |
A0A125SXW3
A8KAF4
G4XH65
H0Y4W6
P03372
Q9UBT1
|
F6KD01
P60484
|
PDB IDs |
1A52
1AKF
1ERE
1ERR
1G50
1GWQ
1GWR
1HCP
1HCQ
1L2I
1PCG
1QKT
1QKU
1R5K
1SJ0
1UOM
1X7E
1X7R
1XP1
1XP6
1XP9
1XPC
1XQC
1YIM
1YIN
1ZKY
2AYR
2B1V
2B1Z
2B23
2BJ4
2FAI
2G44
2G5O
2I0J
2IOG
2IOK
2JF9
2JFA
2LLO
2LLQ
2OCF
2OUZ
2P15
2POG
2Q6J
2Q70
2QA6
2QA8
2QAB
2QE4
2QGT
2QGW
2QH6
2QR9
2QSE
2QXM
2QXS
2QZO
2R6W
2R6Y
2YAT
2YJA
3CBM
3CBO
3CBP
3DT3
3ERD
3ERT
3HLV
3HM1
3L03
3OS8
3OS9
3OSA
3Q95
3UU7
3UUA
3UUC
3UUD
4AA6
4DMA
4IU7
4IUI
4IV2
4IV4
4IVW
4IVY
4IW6
4IW8
4IWC
4IWF
4JC3
4JDD
4MG5
4MG6
4MG7
4MG8
4MG9
4MGA
4MGB
4MGC
4MGD
4O6F
4PP6
4PPP
4PPS
4PXM
4Q13
4Q50
4TUZ
4TV1
4XI3
4ZN7
4ZN9
4ZNH
4ZNS
4ZNT
4ZNU
4ZNV
4ZNW
5AAU
5AAV
5ACC
5AK2
5DI7
5DID
5DIE
5DIG
5DK9
5DKB
5DKE
5DKG
5DKS
5DL4
5DLR
5DMC
5DMF
5DP0
5DRJ
5DRM
5DTV
5DU5
5DUE
5DUG
5DUH
5DVS
5DVV
5DWE
5DWG
5DWI
5DWJ
5DX3
5DXB
5DXE
5DXG
5DXK
5DXM
5DXP
5DXQ
5DXR
5DY8
5DYB
5DYD
5DZ0
5DZ1
5DZ3
5DZH
5DZI
5E0W
5E0X
5E14
5E15
5E19
5E1C
5EGV
5EHJ
5EI1
5EIT
5FQP
5FQR
5FQS
5FQT
5FQV
5GS4
5GTR
5HYR
5JMM
5KCC
5KCD
5KCE
5KCF
5KCT
5KCU
5KCW
5KD9
5KR9
5KRA
5KRC
5KRF
5KRH
5KRI
5KRJ
5KRK
5KRL
5KRM
5KRO
5N10
5T0X
5T1Z
5T92
5T97
5TLD
5TLF
5TLG
5TLL
5TLM
5TLO
5TLP
5TLT
5TLU
5TLV
5TLX
5TLY
5TM1
5TM2
5TM3
5TM4
5TM5
5TM6
5TM7
5TM8
5TM9
5TML
5TMM
5TMO
5TMQ
5TMR
5TMS
5TMT
5TMU
5TMV
5TMW
5TMZ
5TN1
5TN3
5TN4
5TN5
5TN6
5TN7
5TN8
5TN9
5TNB
5U2B
5U2D
5UFW
5UFX
5W9C
5W9D
5WGD
5WGQ
6B0F
6C42
6CBZ
6CHW
6CHZ
6CZN
6D0F
6DF6
6DFN
6HHP
6HKB
6HKF
6HMU
6IAR
6OWC
6PET
6PFM
6PIT
6PSJ
6SBO
6SQ0
6SUO
6TJM
6TL3
6V87
6V8T
6VGH
6VIG
6VJ1
6VJD
6VMU
6VPF
6VPK
6VVP
6WOK
6ZOQ
6ZOR
6ZOS
7JHD
7KBS
7KCA
7KCD
7NFW
|
1D5R
2KYL
4O1V
5BUG
5BZX
5BZZ
|
Enriched GO Terms of Interacting Partners? |
|
|
Tagcloud ? |
|
|
Tagcloud (Difference) ? |
|
|
Tagcloud (Intersection) ? |
|