SLC44A5 and NEGR1

		SLC44A5	NEGR1
Description		solute carrier family 44 member 5	neuronal growth regulator 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Extracellular Region Plasma Membrane Anchored Component Of Membrane
	Molecular Function	Protein Binding Choline Transmembrane Transporter Activity Transmembrane Transporter Activity	Protein Binding
	Biological Process	Phosphatidylcholine Biosynthetic Process Choline Transport Transmembrane Transport	Locomotory Behavior Feeding Behavior Positive Regulation Of Neuron Projection Development Cell-cell Adhesion
Pathways		Synthesis of PC Transport of bile salts and organic acids, metal ions and amine compounds	Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Capecitabine sensitivity ( 22864933) Self-reported tiredness ( 28194004) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 33031748) Serum metabolite ratios in chronic kidney disease ( 29545352) Whole-brain volume (Alzheimer's disease interaction) ( 21116278)	Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) Alcohol consumption (drinks per week) ( 30643258) Allergic rhinitis ( 30013184) Alzheimer's disease (late onset) ( 30820047) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Asthma ( 29273806) Asthma and major depressive disorder ( 31619474) Beef consumption ( 32066663) Bipolar disorder or body mass index ( 31754094) Blood protein levels ( 30072576) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) BMI in smokers ( 28443625) Body mass index ( 31888951 23563607 26426971 19079260 19079261 26961502 23669352 28892062 25673413 20935630 28448500) Body mass index (age <50) ( 26426971) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Body mass index in physically inactive individuals ( 28448500) Body mass index x sex x age interaction (4df test) ( 26426971) Body size at age 10 ( 32376654) Broad depression or major depressive disorder (self-reported) ( 30626913) Cervical high-risk human papilloma virus infection ( 33225922) Childhood body mass index ( 33045005 26604143) Chromium levels ( 26025379) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Depression ( 29700475) Diffusing capacity of carbon monoxide ( 30694715) Experiencing mood swings ( 29500382) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Gastroesophageal reflux disease ( 34187846) General cognitive ability ( 29844566) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heel bone mineral density ( 30598549) Hemostatic factors and hematological phenotypes ( 17903294) Hip circumference ( 25673412) Household income (MTAG) ( 31844048) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Major depressive disorder ( 27479909) Meat-related diet ( 32066663) Menarche (age at onset) ( 25231870) Mental health study participation (completed survey) ( 31263887) Mood instability ( 31168069) Neurociticism ( 29500382) Number of sexual partners ( 30643258) Obesity ( 23563607) Obesity (early onset extreme) ( 23563609) Obesity (extreme) ( 30677029 31888951) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Processed meat consumption ( 32066663) Rosacea symptom severity ( 29771307) Self-reported risk-taking behaviour ( 30271922) Smoking initiation ( 33082346) Smoking status (ever vs never smokers) ( 30643258) Subcutaneous adipose tissue ( 22589738) Systemic lupus erythematosus ( 18204098) Urinary sodium excretion ( 31409800) Venlafaxine response in generalised anxiety disorder (HAMA-A score reduction after 24 weeks) ( 28437668) Vigorous physical activity ( 29899525) Waist circumference ( 25673412) Weight ( 19079260)
Interacting Genes		1 interacting genes: NEGR1	5 interacting genes: LSAMP MIGA1 NTM SAMD13 SLC44A5
Entrez ID		204962	257194
HPRD ID		14580	14820
Ensembl ID		ENSG00000137968	ENSG00000172260
Uniprot IDs		B7Z5Y4 Q8NCS7	Q7Z3B1
PDB IDs			6DLD 6U6T
Enriched GO Terms of Interacting Partners?
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