TSNARE1 and LEPROTL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TSNARE1	LEPROTL1
Description		t-SNARE domain containing 1	leptin receptor overlapping transcript like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endomembrane System Integral Component Of Membrane SNARE Complex	Endosome Integral Component Of Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity	Protein Binding Identical Protein Binding
	Biological Process	Intracellular Protein Transport Vesicle Fusion Vesicle Docking	Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Growth Hormone Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Age at first sexual intercourse ( 34211149) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety ( 33859377) Anxiety/tension (special factor of neuroticism) ( 30867560) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder x sex interaction ( 34099189) Body size at age 10 ( 32376654) Broad depression or schizophrenia ( 30626913) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive decline rate in late mild cognitive impairment ( 26252872) Feeling nervous ( 29500382) Feeling tense ( 29500382) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Intelligence (MTAG) ( 29326435) Mental health study participation (completed survey) ( 31263887) Monoclonal gammopathy of undetermined significance ( 30737484) Schizophrenia ( 28991256 25056061 29483656 30285260 23974872) Systolic blood pressure ( 30224653 30578418)
Interacting Genes		29 interacting genes: CD79A CNIH4 CYB561 DYNLL1 EBP ELOVL4 ELOVL5 GPR152 JAGN1 LEPROTL1 LMNA MFSD14B REEP4 RETREG3 SEC11C SLC10A6 SLC35C2 SNAP29 STX1A TM4SF19 TMEM229B TMEM51 TMEM86B TMX2 TOP1MT VEZT YIPF4 ZDHHC15 ZNF707	74 interacting genes: AGPAT4 ARL13B CD300C CD79A CISD2 CLDN7 CLEC2D CREB3L1 CYP4F2 EDA EHHADH ELOVL4 EMP1 FCER1G FFAR2 FMO1 GJA5 GJA8 GPR152 GPR42 GPX8 JPH1 KCNJ6 KLRG1 LMBR1 LMNA LNX1 LPAR3 LRRC4C MALL MFSD14B MSR1 NAT8 ORMDL3 PAQR8 PDZK1IP1 PEX16 PLP1 PPP3CC RBFA REEP4 REEP6 RNF5 RTP2 SCN3B SDCBP SFXN3 SLC16A2 SLC25A46 SLC30A4 SLC35C2 SLC7A1 SMCO4 SPG21 SSMEM1 STING1 STX12 SYNDIG1 TGFA TMEM11 TMEM14B TMEM19 TMEM237 TMEM248 TMEM42 TMEM50A TMEM50B TMX2 TSNARE1 TSPAN2 TVP23A VAPA YIPF2 ZDHHC15
Entrez ID		203062	23484
HPRD ID		08708	09551
Ensembl ID		ENSG00000171045	ENSG00000104660
Uniprot IDs		E5RHT3 Q6P186 Q96NA8	O95214 Q6FHL7
PDB IDs
Enriched GO Terms of Interacting Partners?
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