STT3B and DDR2

		STT3B	DDR2
Description		STT3 oligosaccharyltransferase complex catalytic subunit B	discoidin domain receptor tyrosine kinase 2
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GO Annotations	Cellular Component	Endoplasmic Reticulum Oligosaccharyltransferase Complex Membrane Integral Component Of Membrane Protein-containing Complex Oligosaccharyltransferase I Complex	Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Actin Cytoskeleton Apical Plasma Membrane Receptor Complex
	Molecular Function	Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding Metal Ion Binding	Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Binding Collagen Binding ATP Binding Protein Tyrosine Kinase Collagen Receptor Activity
	Biological Process	Protein N-linked Glycosylation Glycoprotein Catabolic Process Response To Unfolded Protein Protein N-linked Glycosylation Via Asparagine Ubiquitin-dependent ERAD Pathway Co-translational Protein Modification Post-translational Protein Modification	Ossification Endochondral Bone Growth Cell Adhesion Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Regulation Of Extracellular Matrix Disassembly Positive Regulation Of Fibroblast Migration Peptidyl-tyrosine Phosphorylation Collagen Fibril Organization Regulation Of Bone Mineralization Biomineral Tissue Development Positive Regulation Of Kinase Activity Regulation Of Tissue Remodeling Chondrocyte Proliferation Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Protein Kinase Activity Protein Autophosphorylation Positive Regulation Of Fibroblast Proliferation Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Extracellular Matrix Disassembly
Pathways			Non-integrin membrane-ECM interactions
Drugs			Regorafenib Fostamatinib
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Diabetic retinopathy in type 2 diabetes ( 33607655) Periodontal disease-related phenotype (Socransky) ( 24347629) Urate levels ( 31578528)	Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Dupuytren's disease ( 28886342) Glaucoma (primary open-angle) ( 33627673) Height ( 31562340)
Interacting Genes		11 interacting genes: AADAT CAMLG CYP51A1 DDR2 EIF4H GNMT INCA1 OXSR1 SATB1 SMARCC1 XYLB	6 interacting genes: COL1A1 COL3A1 RGS4 SHC1 SRC STT3B
Entrez ID		201595	4921
HPRD ID		12268	01868
Ensembl ID		ENSG00000163527	ENSG00000162733
Uniprot IDs		Q8TCJ2	A0A024R906 Q16832
PDB IDs		6S7T	2WUH 2Z4F 6FER 7AZB
Enriched GO Terms of Interacting Partners?
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