ELK3 and BPIFA1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ELK3	BPIFA1
Description		ETS transcription factor ELK3	BPI fold containing family A member 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Mitochondrion	Extracellular Region Extracellular Space
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Purine-rich Negative Regulatory Element Binding Sequence-specific Double-stranded DNA Binding	Molecular_function Protein Binding Lipid Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Regulation Of Transcription By RNA Polymerase II Signal Transduction Cell Differentiation Wound Healing Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Immune Response In Nasopharyngeal-associated Lymphoid Tissue Antibacterial Humoral Response Innate Immune Response Regulation Of Liquid Surface Tension Multicellular Organismal Water Homeostasis Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Regulation Of Sodium Ion Transmembrane Transport
Pathways			Antimicrobial peptides
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia in childhood (B cell precursor) ( 29632299 27694927) B-cell acute lymphoblastic leukaemia ( 31767839) Response to inhaled corticosteroid treatment in asthma (change in FEV1) ( 24792382) Small intestine neuroendocrine tumor ( 27492634) Thyroid stimulating hormone levels ( 32769997) Vaginal microbiome composition (community state type) ( 32723796)
Interacting Genes		14 interacting genes: APAF1 APP BPIFA1 CRK CTBP1 ID2 MAPK14 MAPK8 MAPK9 PFDN5 PIAS1 SP4 TCF3 TOP1	50 interacting genes: ALKBH4 COL8A1 CRYBA2 CSKMT DUSP21 ELK3 EML2 FAAP20 FAM222B GADD45GIP1 GCA HCK HNF1B HOXB9 HSFY1 HSFY2 INCA1 INIP KIR2DL4 KRT3 LNX1 MEIS2 MKRN3 MTIF3 NPAS2 NUP54 PATZ1 PEF1 PITX1 PPIH PRR35 PSMB1 RAMAC RSPH14 RTP5 RUSC1 SAMD11 SIRPB1 SNRNP25 TCF7L2 TEPSIN TFG TIAL1 TLE5 TLX3 UBQLN1 UBQLN2 UBQLN4 VPS25 ZNF765
Entrez ID		2004	51297
HPRD ID		02593	07594
Ensembl ID		ENSG00000111145	ENSG00000198183
Uniprot IDs		A0A024RBE2 P41970	Q9NP55
PDB IDs			4KEG 4KGH 4KGO 4N4X 5I7J 5I7K 5I7L
Enriched GO Terms of Interacting Partners?
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