A2M and CYP2C8

  • Number of citations of the paper that reports this interaction (PubMedID 21163940)
  • 36
  • Data Source:
  • BioGRID (two hybrid)

A2M

CYP2C8

Description alpha-2-macroglobulin cytochrome P450 family 2 subfamily C member 8
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood metabolite levels ( 24816252)
  • Gout ( 22179738)
  • Immune response to smallpox vaccine (IL-6) ( 22542470)
  • Low density lipoprotein cholesterol levels ( 33339817)
  • Osteonecrosis of the jaw ( 18594024)
  • Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102)
  • Response to clopidogrel therapy ( 19706858)
  • Serum metabolite levels ( 33031748)
  • Total cholesterol levels ( 33339817)
  • Triglyceride levels in HIV infection ( 33109212)
  • Tuberculosis ( 24057671)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
  • Warfarin maintenance dose ( 23755828)
Interacting Genes 98 interacting genes: ACTB ADAM19 ADAMTS1 AMBP ANXA6 ANXA7 AP1M2 APOE APP ATF7IP ATP1A1 B2M C11orf58 CDC37 CDC42 CDK2AP2 CDKN1A CELA1 CPB2 CTSB CTSE CYP2C18 CYP2C8 DNAJB1 ECSIT EGLN2 ELAVL3 ENO2 EVI5L EXOSC1 FARSA FBXL12 FBXW4 FIS1 GCDH GEM GRB2 H2AX HMOX2 HSP90AA1 HSPA5 HSPB2 IFIT3 IFIT5 IGSF8 IL10 IL1B IL4 KLK1 KLK13 KLK2 KLK3 LCAT LEP LINC02582 LONP1 LRP1 LYZ MAST1 MLST8 MMP2 MYOC NCDN NGF NOS3 NUDT21 OGA PAEP PAXIP1 PDGFA PDGFB PRAM1 PRDX2 RAB3A RAD23A RAP1B RETN RHEB RNF32 RPP14 SEPTIN8 SHBG SLC6A4 SMN1 STAMBPL1 SWSAP1 TGFBI TGIF1 TGM2 TK1 TNFRSF14 TRAPPC5 TSC22D1 TTR TUBA1B TYRO3 UFD1 UMPS 12 interacting genes: A2M APOE BLMH DNAJB1 ECSIT EXOC6 IFIT3 LONP1 MAST1 PSEN1 RIN3 RNF32
Entrez ID 2 1558
HPRD ID 00072 03083
Ensembl ID ENSG00000175899 ENSG00000138115
Uniprot IDs P01023 B7Z1F5 P10632
PDB IDs 1BV8 2P9R 4ACQ 1PQ2 2NNH 2NNI 2NNJ 2VN0
Enriched GO Terms of Interacting Partners?
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