ELAVL2 and RBFOX2

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		ELAVL2	RBFOX2
Description		ELAV like RNA binding protein 2	RNA binding fox-1 homolog 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding	Transcription Corepressor Activity RNA Binding MRNA Binding Protein Binding DNA-binding Transcription Factor Binding
	Biological Process	Regulation Of Transcription, DNA-templated	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Nervous System Development RNA Splicing Regulation Of Definitive Erythrocyte Differentiation RNA Metabolic Process Radial Glia Guided Migration Of Purkinje Cell Intracellular Estrogen Receptor Signaling Pathway Regulation Of Cell Population Proliferation Negative Regulation Of Transcription, DNA-templated Dendrite Morphogenesis Neuromuscular Process Controlling Balance
Pathways		mRNA Splicing - Major Pathway	FGFR2 alternative splicing
Drugs
Diseases
GWAS		Anxiety ( 33859377) Asthma ( 30929738 34103634) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) Attending social / leisure activities ( 34054130) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically inactive individuals ( 28448500) Chronic obstructive pulmonary disease ( 30804561) Feeling guilty ( 29500382) Fulminant type 1 diabetes ( 30552108) General cognitive ability ( 29844566) Glomerular filtration rate change in heart transplantation ( 30160337) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Intelligence (MTAG) ( 29326435) Lung function (FEV1/FVC) ( 30061609) Neurociticism ( 29500382) Neuroticism ( 27089181 29255261 27067015) Physiological traits ( 31902109) Plasma t-tau levels ( 28100725) Remission after SSRI treatment in MDD or neuroticism ( 29559929) Schizophrenia ( 33169155) Sociability score ( 34054130)	Body size at age 10 ( 32376654) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Reading disability or specific language impairment (pleiotropy) ( 25065397) Red cell distribution width ( 32888494) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		10 interacting genes: CDKN2B ELAVL3 ELAVL4 GLIPR2 HNRNPAB HOXC9 IL11RA NR2E3 RBFOX2 SECISBP2	123 interacting genes: APH1A ATN1 ATXN1 ATXN1L BOLL C1orf94 CAMK2A CAMK2B CHAF1A CHERP CLASP2 DAB1 DAZAP2 DDX5 DEDD2 DMRTB1 DNAH5 ELAVL1 ELAVL2 ESR1 ESR2 FAM168B GLIS2 GTF2A1L HNRNPAB HNRNPF HNRNPH1 HNRNPH2 HNRNPK KHDRBS1 KRTAP6-2 MAGED1 MAPK1IP1L MED7 MIR1-1 MIR106A MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-2 MIR140 MIR141 MIR143 MIR155 MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR9-1 MIR9-2 MIR9-3 MIR93 MIRLET7A1 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NAF1 NLGN3 NR2E3 OGT OXER1 PCBP1 POLR3D PSMA3 PSMF1 PTBP1 QKI RBFOX1 RBFOX3 RBM22 RBM23 RBM42 RBPMS RBPMS2 RERE RHOXF2 RNF8 SF3A1 SMN1 SNRPC SPOP TEX37 TOLLIP U2AF2 UBQLN2 VAC14 ZNF137P
Entrez ID		1993	23543
HPRD ID		03396	15231
Ensembl ID		ENSG00000107105	ENSG00000100320
Uniprot IDs		A0A0A0MRX1 Q12926	O43251
PDB IDs			2CQ3
Enriched GO Terms of Interacting Partners?
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