EIF5A and XPO4

Number of citations of the paper that reports this interaction (PubMedID 10944119)
81

Data Source:
HPRD (in vivo, in vitro)

		EIF5A	XPO4
Description		eukaryotic translation initiation factor 5A	exportin 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Annulate Lamellae Nuclear Pore Cytoplasm Endoplasmic Reticulum Membrane Cytosol Membrane	Nuclear Pore Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Binding Translation Elongation Factor Activity Protein Binding U6 SnRNA Binding Ribosome Binding Protein N-terminus Binding	Nuclear Export Signal Receptor Activity Protein Binding
	Biological Process	Translational Elongation Protein Transport Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Translational Elongation Positive Regulation Of Translational Termination Positive Regulation Of Transcription By RNA Polymerase II MRNA Transport Cellular Response To Virus Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator	Protein Export From Nucleus Positive Regulation Of Protein Export From Nucleus
Pathways		Hypusine synthesis from eIF5A-lysine
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Venous thromboembolism ( 31420334)	General cognitive ability ( 29844566) Neuroblastoma or malignant cutaneous melanoma ( 31605138) PR interval ( 30046033 32439900)
Interacting Genes		17 interacting genes: CRX DHPS DOHH GSC2 LBX1 MEI4 MEOX2 PICK1 REL RPL5 SDCBP STUB1 SUMO2 TGM2 XPO1 XPO4 XRN2	4 interacting genes: EIF5A RAN TUBA3C UBQLN1
Entrez ID		1984	64328
HPRD ID		02555	18307
Ensembl ID		ENSG00000132507	ENSG00000132953
Uniprot IDs		P63241	Q9C0E2
PDB IDs		1FH4 3CPF 5DLQ
Enriched GO Terms of Interacting Partners?
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