EEF2KMT and HPRT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EEF2KMT	HPRT1
Description		eukaryotic elongation factor 2 lysine methyltransferase	hypoxanthine phosphoribosyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Protein-containing Complex	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Protein-lysine N-methyltransferase Activity	Nucleotide Binding Magnesium Ion Binding Hypoxanthine Phosphoribosyltransferase Activity Protein Binding Identical Protein Binding Guanine Phosphoribosyltransferase Activity
	Biological Process	Protein Methylation Peptidyl-lysine Trimethylation	T Cell Mediated Cytotoxicity Response To Amphetamine Purine Nucleotide Biosynthetic Process Purine Ribonucleoside Salvage Adenine Salvage Guanine Salvage Grooming Behavior Locomotory Behavior Striatum Development Cerebral Cortex Neuron Differentiation Central Nervous System Neuron Development GMP Salvage IMP Salvage Dopamine Metabolic Process Hypoxanthine Salvage AMP Salvage Positive Regulation Of Dopamine Metabolic Process GMP Catabolic Process IMP Metabolic Process Hypoxanthine Metabolic Process Lymphocyte Proliferation Dendrite Morphogenesis Protein Homotetramerization
Pathways		Protein methylation	Purine salvage
Drugs			Mercaptopurine 5-O-phosphono-alpha-D-ribofuranosyl diphosphate 5-monophosphate-9-beta-D-ribofuranosyl xanthine 3H-pyrazolo[4,3-d]pyrimidin-7-ol 9-Deazaguanine
Diseases
GWAS			Estimated glomerular filtration rate ( 31015462)
Interacting Genes		12 interacting genes: HPRT1 IFT88 KIAA1328 LNX1 NR0B1 PICK1 PRKAR1B PRTFDC1 TRIP13 ZNF213 ZNF35 ZNF620	12 interacting genes: EEF2KMT EFCAB3 FANCA FXR1 GNMT ISCU NTAQ1 PCNT PRTFDC1 SDCBP SPG21 SREK1IP1
Entrez ID		196483	3251
HPRD ID		18018	02388
Ensembl ID		ENSG00000118894	ENSG00000165704
Uniprot IDs		K7ES84 Q96G04	A0A140VJL3 P00492
PDB IDs			1BZY 1D6N 1HMP 1Z7G 2VFA 3GEP 3GGC 3GGJ 4IJQ 4KN6 4RAB 4RAC 4RAD 4RAN 4RAO 4RAQ 5BRN 5BSK 5HIA 5W8V 6BNJ
Enriched GO Terms of Interacting Partners?
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