Description |
epidermal growth factor receptor |
mitogen-activated protein kinase 14 |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Minocycline
- Dasatinib
- 4-[5-[2-(1-phenyl-ethylamino)-pyrimidin-4-yl]-1-methyl-4-(3-trifluoromethylphenyl)-1H-imidazol-2-yl]-piperidine
- N-[(3Z)-5-Tert-butyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-ylidene]-N'-(4-chlorophenyl)urea
- 1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperidin-4-Yl-3,4-Dihydroquinolin-2(1h)-One
- Inhibitor of P38 Kinase
- 6((S)-3-Benzylpiperazin-1-Yl)-3-(Naphthalen-2-Yl)-4-(Pyridin-4-Yl)Pyrazine
- 3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine
- 1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea
- 3-(Benzyloxy)Pyridin-2-Amine
- 1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One
- 4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline
- Doramapimod
- 2-Chlorophenol
- 4-(Fluorophenyl)-1-Cyclopropylmethyl-5-(2-Amino-4-Pyrimidinyl)Imidazole
- SB220025
- 4-(2-HYDROXYBENZYLAMINO)-N-(3-(4-FLUOROPHENOXY)PHENYL)PIPERIDINE-1-SULFONAMIDE
- Triazolopyridine
- KC706
- Talmapimod
- VX-702
- R-1487
- 1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea
- N-ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide
- N-[2-methyl-5-(methylcarbamoyl)phenyl]-2-{[(1R)-1-methylpropyl]amino}-1,3-thiazole-5-carboxamide
- Neflamapimod
- N-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide
- 4-PHENOXY-N-(PYRIDIN-2-YLMETHYL)BENZAMIDE
- 4-[5-(3-IODO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-1H-IMIDAZOL-4-YL]-PYRIDINE
- N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide
- 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE
- 4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-yl}-1,3-thiazole-2-carbaldehyde
- N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamide
- N-(cyclopropylmethyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide
- N~3~-cyclopropyl-N~4~'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide
- PH-797804
- 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine
- SD-0006
- N-(3-TERT-BUTYL-1H-PYRAZOL-5-YL)-N'-{4-CHLORO-3-[(PYRIDIN-3-YLOXY)METHYL]PHENYL}UREA
- N-[4-CHLORO-3-(PYRIDIN-3-YLOXYMETHYL)-PHENYL]-3-FLUORO-
- 3-FLUORO-5-MORPHOLIN-4-YL-N-[3-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-5-YL]BENZAMIDE
- 3-fluoro-N-1H-indol-5-yl-5-morpholin-4-ylbenzamide
- 3-(1-NAPHTHYLMETHOXY)PYRIDIN-2-AMINE
- 3-(2-CHLOROPHENYL)-1-(2-{[(1S)-2-HYDROXY-1,2-DIMETHYLPROPYL]AMINO}PYRIMIDIN-4-YL)-1-(4-METHOXYPHENYL)UREA
- 8-(2-CHLOROPHENYLAMINO)-2-(2,6-DIFLUOROPHENYLAMINO)-9-ETHYL-9H-PURINE-1,7-DIIUM
- 2-(2,6-DIFLUOROPHENOXY)-N-(2-FLUOROPHENYL)-9-ISOPROPYL-9H-PURIN-8-AMINE
- N,4-dimethyl-3-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide
- N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide
- N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethyl)amino]quinazolin-6-yl}benzamide
- 6-[4-(2-fluorophenyl)-1,3-oxazol-5-yl]-N-(1-methylethyl)-1,3-benzothiazol-2-amine
- 2-(ETHOXYMETHYL)-4-(4-FLUOROPHENYL)-3-[2-(2-HYDROXYPHENOXY)PYRIMIDIN-4-YL]ISOXAZOL-5(2H)-ONE
- [5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL][3-(PIPERIDIN-4-YLOXY)PHENYL]METHANONE
- [5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL](3-{[(2R)-2,3-DIHYDROXYPROPYL]OXY}PHENYL)METHANONE
- 4-[4-(4-Fluorophenyl)-2-[4-[(R)-methylsulfinyl]phenyl]-1H-imidazol-5-yl]pyridine
- 4-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLE
- 3-FLUORO-5-MORPHOLIN-4-YL-N-[1-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-6-YL]BENZAMIDE
- Fostamatinib
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Diseases |
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GWAS |
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- Foot ulcer in diabetes and neuropathy ( 28672053)
- Height ( 33713608)
- Waist circumference adjusted for body mass index ( 34021172)
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Interacting Genes |
412 interacting genes:
ABL2
ACTA1
ADRM1
AGTR1
AHNAK
AHSA1
AIP
AKAP12
ALCAM
ALDOA
AMH
ANKS1A
ANKS1B
ANXA1
AOPEP
AP2B1
APBA3
APBB1
APBB3
APP
APPL1
AR
AREG
ARF4
ARHGEF12
ARHGEF7
ARRB2
ATIC
ATP1A1
ATP1B1
ATP5F1C
AXL
B4GALT1
BAIAP2
BCAR3
BLK
BLNK
BMX
BTC
CALM1
CALM2
CALM3
CAMK2A
CAMK2G
CAMLG
CASP1
CAV1
CAV2
CAV3
CBL
CBLB
CBLC
CCDC88A
CD44
CD59
CD82
CDC25A
CDC34
CDH1
CDH5
CDK1
CEACAM1
CEBPB
CEND1
CFL1
CLNK
CLTA
CLTCL1
CMTM8
CNOT9
CNTN2
COL9A3
CRK
CSRP1
CTNNB1
CTNND1
CTTN
CYLC2
DCBLD2
DCN
DCTN2
DEGS1
DNAJC4
DOK2
DOK4
DOK5
DOK6
DUSP19
DUSP3
DYNC1H1
EGF
ELF3
EPB41
EPHA2
EPPK1
EPS15
EPS8
ERBB2
ERBB3
ERBB4
EREG
ERRFI1
ESR1
EZR
FAH
FANCC
FAS
FBXO25
FER
FES
FGR
FKBP4
FKBP8
FN1
FRAT2
FRK
GAB1
GABARAPL2
GAPDH
GGA1
GGA3
GJB1
GNAI2
GNAS
GOT1
GPM6B
GPNMB
GRAP2
GRB10
GRB14
GRB2
GRB7
GRIN2B
GRK2
H3-4
HBEGF
HCK
HDAC6
HDAC7
HEBP1
HEMGN
HEXIM1
HGS
HOXC10
HPN
HSH2D
HSP90AA1
HSP90AB1
HSP90B1
HSPA1A
HSPA4
HSPA8
HTT
ICAM1
IKBKG
IL13RA2
IL5RA
ILKAP
INPPL1
IQGAP1
IRS1
IRS4
ITGA5
ITGB1
ITGB2
ITK
ITSN2
JAK2
JUP
KCTD9P2
KEAP1
KRT17
KRT18
KRT7
KRT8
LAT
LCK
LCP2
LINC01139
LRP1
LRRK1
LYN
MAP2K1
MAP3K12
MAP3K14
MAP3K3
MAP4K1
MAPK1
MAPK14
MAPK3
MAPK8
MAPK8IP1
MAPK8IP2
MAPK9
MAPT
MAST1
MATR3
MDH1
MEGF6
MET
MGARP
MIF
MOB4
MT-CO2
MTDH
MUC1
MUC4
NANS
NCAM1
NCK1
NCK2
NDN
NEDD4
NF2
NIBAN2
NR3C1
NRG1
NTRK2
NUMB
NUMBL
OAZ1
OLFM1
PAK1
PCNA
PDCD6IP
PDGFRA
PDGFRB
PDK3
PDP1
PFKP
PHKG1
PIK3C2A
PIK3C2B
PIK3CA
PIK3R1
PIK3R2
PIK3R3
PIM1
PIN4
PITPNA
PKIA
PLCG1
PLCG2
PLD1
PLD2
PLEC
PLSCR1
PML
POM121L12
PPARG
PPM1A
PPM1B
PPP2CB
PPP3CB
PPP5C
PRCC
PRDX1
PRKACA
PRKAR1A
PRKAR1B
PRKCA
PRKCB
PRKCD
PRKCE
PRKCZ
PRKD1
PSMA7
PSMD4
PTGDS
PTK2
PTK2B
PTK6
PTPN1
PTPN11
PTPN12
PTPN18
PTPN2
PTPN20
PTPN22
PTPN6
PTPN7
PTPRB
PTPRH
PTPRJ
PTPRR
PTPRS
PTPRT
PTPRU
RAB31
RAB3A
RAF1
RAP1GDS1
RAPGEF1
RASA1
RGS16
RGS2
RGS4
RIN1
RIN2
RIPK1
RNF115
RNF126
RNF144A
RRAD
RUSC2
S100A4
S100A7
S100A9
SCAMP1
SCAMP3
SEC13
SELENOP
SFN
SGSM2
SH2B1
SH2B2
SH2B3
SH2D1A
SH2D1B
SH2D2A
SH2D3A
SH2D3C
SH3BGRL3
SH3GL3
SHB
SHC1
SHC2
SHC3
SHC4
SHD
SHE
SLA
SLA2
SLC3A2
SLC9A3R1
SMURF2
SNCA
SNRPD2
SNX1
SNX2
SNX4
SNX6
SNX9
SOCS1
SOCS2
SOCS3
SOCS4
SOCS5
SOCS6
SOCS7
SORBS2
SOS1
SOS2
SPARCL1
SPCS2
SRC
STAG3L4
STAM2
STAP1
STAP2
STAT1
STAT2
STAT3
STAT5A
STAT5B
STIP1
STX17
STYX
SUPT6H
SYK
TAB1
TEC
TGFA
TGFB1
TJP1
TLN1
TLR2
TMCO3
TNC
TNFRSF1A
TNK2
TNS1
TNS2
TNS3
TNS4
TPI1
TPM1
TRAF2
TRMO
TRPV1
TSTD2
TUBA1A
TUBA4A
TXK
TXN
UBB
UBE2V2
UROD
VAPA
VAV1
VAV2
VAV3
WASF3
WASL
XRCC6
YES1
YWHAB
YWHAQ
YWHAZ
ZAP70
ZNF510
ZPR1
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168 interacting genes:
AIMP1
AKT1
ARNT
ATF2
BCL2
BCL2L1
BICD1
BMI1
CCDC14
CCDC97
CCND2
CD4
CDC25A
CDC25B
CDC25C
CDK4
CDK6
CDKN2A
CDT1
CDX2
CENPC
CEP164
COPS5
CREB1
CSNK2A1
CSNK2A2
CSNK2B
DAB1
DDIT3
DUSP1
DUSP10
DUSP16
DUSP2
DUSP22
DUSP4
DUSP7
DUSP9
DYRK1B
EEA1
EEF1A1
EEF2K
EGFR
EIF4EBP1
ELK1
ELK3
EPB42
EPHA2
EPS15
ESR1
ETV1
FGFR4
FKBP8
FLNA
GADD45A
GATA3
GDF15
GMFB
GORASP2
GRB2
HDAC3
HIVEP1
HNF4A
HSF4
HSPB1
HTRA2
ILKAP
INTS6L
IRAK1
JDP2
JUN
JUNB
KAT2A
KAT2B
KMT2C
KRT18
KRT8
LATS2
LIMK1
MAFA
MAP2K1
MAP2K3
MAP2K4
MAP2K6
MAP2K7
MAP3K10
MAP3K7
MAPK1
MAPK3
MAPK8
MAPKAPK2
MAPKAPK3
MAPKAPK5
MAPT
MARS1
MAX
MBP
MEF2A
MEF2C
MEF2D
METTL3
MIDEAS
MITF
MKNK1
MKNK2
MOB3B
MUC12
MYC
NCOA3
NF2
NFATC1
NFATC4
NFIC
NKTR
NRL
NUP153
PAK6
PHC2
PI4K2B
PLA2G4A
PLG
PML
PPARGC1A
PPP4R3A
PTPN7
RB1
RBSN
RELA
RET
ROBO1
RPL22
RPL41
RPS6KA4
RPS6KA5
S100A9
SCN8A
SH2D1A
SHC1
SLC9A1
SMAD3
SMAD7
SMARCD3
SNAPIN
SP7
SPAG9
SPTBN1
SQSTM1
SRPK1
SRSF5
STAT1
STAT4
STK11
STK39
SUPT20H
TAB1
TCF20
TFCP2
TLE5
TMEM63B
TNFRSF4
TP53
TRAF6
TSC1
UGT2B10
ULK1
YY1AP1
ZFP36L1
ZNF142
ZNHIT1
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Entrez ID |
1956 |
1432 |
HPRD ID |
00579 |
02619 |
Ensembl ID |
ENSG00000146648
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ENSG00000112062
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Uniprot IDs |
B7Z2I3
E7BSV0
E9PFD7
F2YGG7
P00533
Q504U8
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A0A024RD15
B4E0K5
L7RSM2
Q16539
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PDB IDs |
1DNQ
1DNR
1IVO
1M14
1M17
1MOX
1NQL
1XKK
1YY9
1Z9I
2EB2
2EB3
2EXP
2EXQ
2GS2
2GS6
2GS7
2ITN
2ITO
2ITP
2ITQ
2ITT
2ITU
2ITV
2ITW
2ITX
2ITY
2ITZ
2J5E
2J5F
2J6M
2JIT
2JIU
2JIV
2KS1
2M0B
2M20
2N5S
2RF9
2RFD
2RFE
2RGP
3B2U
3B2V
3BEL
3BUO
3C09
3G5V
3G5Y
3GOP
3GT8
3IKA
3LZB
3NJP
3OB2
3OP0
3P0Y
3PFV
3POZ
3QWQ
3UG1
3UG2
3VJN
3VJO
3VRP
3VRR
3W2O
3W2P
3W2Q
3W2R
3W2S
3W32
3W33
4G5J
4G5P
4HJO
4I1Z
4I20
4I21
4I22
4I23
4I24
4JQ7
4JQ8
4JR3
4JRV
4KRL
4KRM
4KRO
4KRP
4LI5
4LL0
4LQM
4LRM
4R3P
4R3R
4R5S
4RIW
4RIX
4RIY
4RJ4
4RJ5
4RJ6
4RJ7
4RJ8
4TKS
4UIP
4UV7
4WD5
4WKQ
4WRG
4ZAU
4ZJV
4ZSE
5C8K
5C8M
5C8N
5CAL
5CAN
5CAO
5CAP
5CAQ
5CAS
5CAU
5CAV
5CNN
5CNO
5CZH
5CZI
5D41
5EDP
5EDQ
5EDR
5EM5
5EM6
5EM7
5EM8
5FED
5FEE
5FEQ
5GMP
5GNK
5GTY
5GTZ
5HCX
5HCY
5HCZ
5HG5
5HG7
5HG8
5HG9
5HIB
5HIC
5J9Y
5J9Z
5JEB
5LV6
5SX4
5SX5
5U8L
5UG8
5UG9
5UGA
5UGB
5UGC
5UWD
5WB7
5WB8
5X26
5X27
5X28
5X2A
5X2C
5X2F
5X2K
5XDK
5XDL
5XGM
5XGN
5XWD
5Y25
5Y9T
5YU9
5ZTO
5ZWJ
6ARU
6B3S
6D8E
6DUK
6JRJ
6JRK
6JRX
6JWL
6JX0
6JX4
6JXT
6JZ0
6LUB
6LUD
6P1D
6P1L
6P8Q
6S89
6S8A
6S9B
6S9C
6S9D
6TFU
6TFV
6TFW
6TFY
6TFZ
6TG0
6TG1
6V5N
6V5P
6V66
6V6K
6V6O
6VH4
6VHN
6VHP
6Z4B
6Z4D
7A2A
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1A9U
1BL6
1BL7
1BMK
1DI9
1IAN
1KV1
1KV2
1M7Q
1OUK
1OUY
1OVE
1OZ1
1R39
1R3C
1W7H
1W82
1W83
1W84
1WBN
1WBO
1WBS
1WBT
1WBV
1WBW
1WFC
1YQJ
1ZYJ
1ZZ2
1ZZL
2BAJ
2BAK
2BAL
2BAQ
2FSL
2FSM
2FSO
2FST
2GFS
2I0H
2LGC
2NPQ
2OKR
2ONL
2QD9
2RG5
2RG6
2Y8O
2YIS
2YIW
2YIX
2ZAZ
2ZB0
2ZB1
3BV2
3BV3
3BX5
3C5U
3CTQ
3D7Z
3D83
3DS6
3DT1
3E92
3E93
3FC1
3FI4
3FKL
3FKN
3FKO
3FL4
3FLN
3FLQ
3FLS
3FLW
3FLY
3FLZ
3FMH
3FMJ
3FMK
3FML
3FMM
3FMN
3FSF
3FSK
3GC7
3GCP
3GCQ
3GCS
3GCU
3GCV
3GFE
3GI3
3HA8
3HEC
3HEG
3HL7
3HLL
3HP2
3HP5
3HRB
3HUB
3HUC
3HV3
3HV4
3HV5
3HV6
3HV7
3HVC
3IPH
3ITZ
3IW5
3IW6
3IW7
3IW8
3K3I
3K3J
3KF7
3KQ7
3L8S
3L8X
3LFA
3LFB
3LFC
3LFD
3LFE
3LFF
3LHJ
3MGY
3MH0
3MH1
3MH2
3MH3
3MPA
3MPT
3MVL
3MVM
3MW1
3NEW
3NNU
3NNV
3NNW
3NNX
3NWW
3O8P
3O8T
3O8U
3OBG
3OBJ
3OC1
3OCG
3OD6
3ODY
3ODZ
3OEF
3PG3
3QUD
3QUE
3RIN
3ROC
3S3I
3S4Q
3U8W
3UVP
3UVQ
3UVR
3ZS5
3ZSG
3ZSH
3ZSI
3ZYA
4A9Y
4AA0
4AA4
4AA5
4AAC
4DLI
4DLJ
4E5A
4E5B
4E6A
4E6C
4E8A
4EH2
4EH3
4EH4
4EH5
4EH6
4EH7
4EH8
4EH9
4EHV
4EWQ
4F9W
4F9Y
4FA2
4GEO
4KIN
4KIP
4KIQ
4L8M
4R3C
4ZTH
5ETA
5ETC
5ETF
5ETI
5ML5
5MTX
5MTY
5MZ3
5N63
5N64
5N65
5N66
5N67
5N68
5O8U
5O8V
5OMG
5OMH
5TBE
5TCO
5WJJ
5XYX
5XYY
6ANL
6HWT
6HWU
6HWV
6M95
6M9L
6OHD
6QDZ
6QE1
6QYX
6RFO
6SFI
6SFJ
6SFK
6SFO
6TCA
6ZQS
6ZWP
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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