EFNB2 and PDZRN3

Number of citations of the paper that reports this interaction (PubMedID 15458844)
74

Data Source:
HPRD (two hybrid)

		EFNB2	PDZRN3
Description		ephrin B2	PDZ domain containing ring finger 3
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Adherens Junction Focal Adhesion Glutamatergic Synapse Integral Component Of Presynaptic Membrane	Cytoplasm Neuromuscular Junction
	Molecular Function	Virus Receptor Activity Protein Binding Ephrin Receptor Binding	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cell Migration Involved In Sprouting Angiogenesis Cell Adhesion Cell-cell Signaling Axon Guidance Positive Regulation Of Cell Population Proliferation Anatomical Structure Morphogenesis Negative Regulation Of Neuron Projection Development Viral Entry Into Host Cell Ephrin Receptor Signaling Pathway Blood Vessel Morphogenesis Regulation Of Chemotaxis Presynapse Assembly Positive Regulation Of Neuron Death Positive Regulation Of Cardiac Muscle Cell Differentiation	Neuromuscular Junction Development Protein Ubiquitination
Pathways		EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells
Drugs
Diseases
GWAS		BMI x environmental factors (excluding physical activity) interaction ( 33654129) BMI x environmental factors (including physical activity) interaction ( 33654129) Left superior temporal gyrus thickness (schizophrenia interaction) ( 26249676) Metabolite levels ( 23823483) Pediatric autoimmune diseases ( 26301688) Subcutaneous adipose tissue ( 26480920)	Dialysis-related mortality ( 21546767) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) Mercury levels ( 26025379) Mitochondrial DNA copy number (white blood cells) ( 30704525) PR interval ( 30679814 30046033 32439900)
Interacting Genes		23 interacting genes: ANKRD46 DLG4 EPHA3 EPHA4 EPHB1 EPHB2 EPHB4 EPHB6 GRIP1 GRM1 GRM5 HOMER1 NCK2 PDZRN3 PECAM1 PICK1 PSEN1 PTPN13 RELN RGS3 RHBDL2 SDCBP SRC	7 interacting genes: BMPR2 EFNB2 LNX1 LNX2 RPS6KA1 SLC5A8 UBE2D2
Entrez ID		1948	23024
HPRD ID		02754	15115
Ensembl ID		ENSG00000125266	ENSG00000121440
Uniprot IDs		P52799	B7Z2I8 B7Z5Q3 B7Z5X9 B7ZAG0 E7ENB6 Q9UPQ7
PDB IDs		2HLE 2I85 2VSK 2VSM 2WO2 3GXU 4UF7 6P7Y 6PDL	1UHP 1WH1
Enriched GO Terms of Interacting Partners?
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