AHCY and C1orf50

Number of citations of the paper that reports this interaction (PubMedID 26186194)
524

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, two hybrid)

		AHCY	C1orf50
Description		adenosylhomocysteinase	chromosome 1 open reading frame 50
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Melanosome Neuron Projection Extracellular Exosome	Cellular_component
	Molecular Function	Adenosylhomocysteinase Activity Protein Binding Adenyl Nucleotide Binding Identical Protein Binding NAD Binding	Protein Binding Identical Protein Binding
	Biological Process	Response To Hypoxia Chronic Inflammatory Response To Antigenic Stimulus One-carbon Metabolic Process Response To Nutrient S-adenosylhomocysteine Catabolic Process S-adenosylmethionine Cycle Circadian Sleep/wake Cycle	Biological_process
Pathways		Methylation Sulfur amino acid metabolism Metabolism of ingested SeMet, Sec, MeSec into H2Se Defective AHCY causes HMAHCHD
Drugs		(1'R,2'S)-9-(2-Hydroxy-3'-Keto-Cyclopenten-1-yl)Adenine 3'-Oxo-Adenosine D-Eritadenine Copper
Diseases
GWAS		Fish- and plant-related diet ( 32066663) Heel bone mineral density ( 30598549) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Liver enzyme levels (alanine transaminase) ( 33972514) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Vitiligo ( 27723757) Walking pace ( 33128006)
Interacting Genes		10 interacting genes: ANKRD40 APPBP2 C1orf50 FXR1 POT1 PXN RBFOX1 TERF1 UFL1 YWHAQ	17 interacting genes: ADCY4 AHCY APPBP2 CLSPN CRX EIF2B1 EPM2AIP1 EXO5 INCA1 LRP2BP MEOX1 MEOX2 NTAQ1 PPCS REL TCF4 ZMYND12
Entrez ID		191	79078
HPRD ID		01621	14714
Ensembl ID		ENSG00000101444	ENSG00000164008
Uniprot IDs		A0A384MTQ3 P23526 Q1RMG2	Q9BV19
PDB IDs		1A7A 1LI4 3NJ4 4PFJ 4PGF 4YVF 5W49 5W4B
Enriched GO Terms of Interacting Partners?
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