AGTR2 and MTUS1

Number of citations of the paper that reports this interaction (PubMedID 15123706)
48

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		AGTR2	MTUS1
Description		angiotensin II receptor type 2	microtubule associated scaffold protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Perinuclear Region Of Cytoplasm	Extracellular Space Nucleus Nucleolus Cytoplasm Mitochondrion Golgi Apparatus Microtubule Organizing Center Spindle Microtubule Plasma Membrane Microtubule Cytoskeleton
	Molecular Function	G Protein-coupled Receptor Activity Angiotensin Type II Receptor Activity Protein Binding Receptor Antagonist Activity	Microtubule Binding
	Biological Process	Positive Regulation Of Cytokine Production Blood Vessel Remodeling Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin Renin-angiotensin Regulation Of Aldosterone Production Cellular Sodium Ion Homeostasis Inflammatory Response Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger Nitric Oxide Mediated Signal Transduction Brain Development Regulation Of Blood Pressure Positive Regulation Of Cell Population Proliferation Negative Regulation Of Heart Rate Negative Regulation Of Norepinephrine Secretion Cerebellar Cortex Development Negative Regulation Of Cell Growth Negative Regulation Of Icosanoid Secretion Positive Regulation Of Phosphoprotein Phosphatase Activity Intracellular Signal Transduction Positive Regulation Of Renal Sodium Excretion Aldosterone Secretion Angiotensin-activated Signaling Pathway Regulation Of Protein Import Into Nucleus Vasodilation Dopamine Biosynthetic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of Fibroblast Proliferation Positive Regulation Of Nitric-oxide Synthase Activity Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Kidney Morphogenesis Cell Growth Involved In Cardiac Muscle Cell Development Cellular Response To Dexamethasone Stimulus Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Negative Regulation Of Signaling Receptor Activity Positive Regulation Of Extrinsic Apoptotic Signaling Pathway	Regulation Of Macrophage Chemotaxis
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events
Drugs		Tasosartan CYT006-AngQb
Diseases
GWAS		Cystic fibrosis severity ( 21602797) Gestational age at birth (maternal effect) ( 28877031) Lung disease severity in cystic fibrosis ( 26417704) Offspring birth weight ( 31043758) Preterm birth (maternal effect) ( 28877031) Type 2 diabetes ( 29358691 30130595)	Hippocampal volume in normal cognition ( 29274321) PR interval ( 32439900)
Interacting Genes		11 interacting genes: ACE AGT AGTRAP ERBB3 ERBIN GNAI2 GNAI3 MTUS1 PIK3CB SNTA1 ZBTB16	7 interacting genes: AGTR2 FBXO7 ORC4 SKP1 SOX7 STX5 STX7
Entrez ID		186	57509
HPRD ID		02071	11376
Ensembl ID		ENSG00000180772	ENSG00000129422
Uniprot IDs		P50052	Q9ULD2
PDB IDs		5UNF 5UNG 5UNH 6JOD
Enriched GO Terms of Interacting Partners?
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