DTNA and UTRN

Number of citations of the paper that reports this interaction (PubMedID 24981860)
22

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro)

		DTNA	UTRN
Description		dystrobrevin alpha	utrophin
Image
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Plasma Membrane Cell Junction Axon Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Protein-containing Complex Sarcolemma Intermediate Filament Cytoskeleton Synapse	Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Membrane Cell Junction Filopodium Cortical Actin Cytoskeleton Filopodium Membrane Neuromuscular Junction Protein-containing Complex Sarcolemma Cell Projection Postsynaptic Membrane Extracellular Exosome Contractile Ring
	Molecular Function	Protein Binding Zinc Ion Binding Phosphatase Binding PDZ Domain Binding	Actin Binding Integrin Binding Protein Binding Zinc Ion Binding Vinculin Binding Protein Kinase Binding Actin Filament Binding
	Biological Process	Striated Muscle Contraction Signal Transduction Chemical Synaptic Transmission Neuromuscular Synaptic Transmission Synaptic Signaling	Positive Regulation Of Cell-matrix Adhesion Muscle Contraction Muscle Organ Development Actin Cytoskeleton Organization Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways			EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs			Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) PR interval ( 32439900) Urate levels in overweight individuals ( 25811787)	Age at first sexual intercourse ( 34211149) Loneliness (multivariate analysis) ( 27629369) Multisite chronic pain ( 33830993 31194737) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954) Refractive error ( 32231278) Remission after SSRI treatment in MDD or openness ( 29559929) Response to fenofibrate (triglyceride levels) ( 27002377) Response to mepolizumab in severe asthma ( 29229094) Response to SSRI in MDD or openness ( 29559929) Restless legs syndrome in migraine without aura ( 32918390)
Interacting Genes		17 interacting genes: ACTA1 APPL1 DMD DRP2 DTNBP1 GFI1B HMG20A KCNJ12 SNTA1 SNTB1 SNTB2 SNTG1 SNTG2 STAT3 SYNC SYNM UTRN	22 interacting genes: ACTA1 ACTN2 C1QTNF9 CALM1 DAG1 DISC1 DMD DRP2 DTNA DTNB ITGB1BP1 MARCHF5 MARK2 NUP98 PGM5 PRKACA PTEN PTPN12 SASH1 SNTA1 SNTB1 SNTB2
Entrez ID		1837	7402
HPRD ID		03141	00547
Ensembl ID		ENSG00000134769	ENSG00000152818
Uniprot IDs		A0A024RC32 B7Z3X3 Q9Y4J8	P46939 Q6LBS5
PDB IDs		2E5R	1BHD 1QAG 6M5G
Enriched GO Terms of Interacting Partners?
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