DSCAM and KCNJ15

		DSCAM	KCNJ15
Description		DS cell adhesion molecule	potassium inwardly rectifying channel subfamily J member 15
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Membrane Axon Dendrite Growth Cone Neuronal Cell Body Synapse	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding Cell-cell Adhesion Mediator Activity Protein Tyrosine Kinase Binding Netrin Receptor Binding	Inward Rectifier Potassium Channel Activity Protein Binding
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Negative Regulation Of Cell Adhesion Nervous System Development Axon Guidance Synapse Assembly Locomotory Behavior Retina Layer Formation Netrin-activated Signaling Pathway Positive Regulation Of Phosphorylation Dendrite Morphogenesis Positive Regulation Of Axon Extension Involved In Axon Guidance Post-embryonic Retina Morphogenesis In Camera-type Eye Camera-type Eye Photoreceptor Cell Differentiation Dendrite Self-avoidance	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		DSCAM interactions DSCAM interactions	Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs			Yohimbine Butamben
Diseases
GWAS		Adult body size ( 32376654) Anxiety in major depressive disorder ( 24047446) Blood protein levels ( 30072576) Fasting plasma glucose ( 31170924) Feeling nervous ( 29500382) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Gut microbiota relative abundance (Prevotella) ( 33208821) Hallux valgus ( 32131869) Intracranial aneurysm ( 30823506) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Low hand grip strength (60 years and older) (EWGSOP) ( 33510174) Mild to moderate chronic kidney disease ( 31178898) Neutrophil count ( 21507922) Non-small cell lung cancer (survival) ( 21079520) Obesity-related traits ( 23251661) Refractive error ( 32231278) Schizophrenia ( 34099189) Schizophrenia x sex interaction ( 34099189) Spontaneous preterm birth without premature rupture of membranes ( 31194736) Systemising ( 31508503) Tuberculosis ( 24057671) Worry/vulnerability (special factor of neuroticism) ( 30867560)	Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Body shape index ( 34021172) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Metabolite levels ( 23823483) Monocyte count ( 32888494) Non-response to antidepressants and depression ( 27622933) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		6 interacting genes: KCNJ15 PAK1 PCP4 PIH1D2 RCAN1 TTC3	16 interacting genes: CBR3 CTSE DSCAM IL16 KCNE1 KCNJ16 KCNJ2 KCNJ5 LRP8 MTCH1 PATJ SLC39A2 SNTA1 SON TOR1B TTC3
Entrez ID		1826	3772
HPRD ID		03953	03659
Ensembl ID		ENSG00000171587	ENSG00000157551
Uniprot IDs		O60469	Q99712
PDB IDs		6ZR7
Enriched GO Terms of Interacting Partners?
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