ATN1 and LTBP1

Number of citations of the paper that reports this interaction (PubMedID 16713569)
337

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATN1	LTBP1
Description		atrophin 1	latent transforming growth factor beta binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Cell Junction Perinuclear Region Of Cytoplasm	Microfibril Extracellular Region Endoplasmic Reticulum Lumen Extracellular Matrix Protein-containing Complex Collagen-containing Extracellular Matrix
	Molecular Function	Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding	Transforming Growth Factor Beta-activated Receptor Activity Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Transforming Growth Factor Beta Binding Microfibril Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Neuron Apoptotic Process	Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Sequestering Of TGFbeta In Extracellular Matrix Regulation Of Transforming Growth Factor Beta Activation
Pathways		Regulation of PTEN gene transcription	Molecules associated with elastic fibres Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Arthritis (juvenile idiopathic) ( 34101054) Carpal tunnel syndrome ( 30833571) Central corneal thickness ( 32528159 29760442) Diverticular disease ( 30177863) Height ( 28552196 20881960 25282103 25429064 19893584 23563607 31562340 20189936) Hip circumference adjusted for BMI ( 34021172 25673412) Immune reponse to smallpox (secreted IFN-alpha) ( 22610502) Immune response to smallpox vaccine (IL-6) ( 22610502) Intraocular pressure ( 29617998 29785010 29235454) Knee osteoarthritis ( 30374069) Male-pattern baldness ( 28196072) Optic disc size ( 31809533) Rosacea symptom severity ( 29771307) Total cholesterol levels ( 33339817) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 34021172 25673412 28448500)
Interacting Genes		125 interacting genes: AGRN ALG13 ARF3 ATRX BAG3 BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CENPJ CHRD CRACR2A CRIP2 CSNK2A1 CTNND2 DGCR6L DMPK DMRT3 DVL1 DVL2 ECM1 EFEMP1 EFEMP2 ETNK2 EWSR1 FBLN1 FBLN2 FBLN5 FXR1 FXR2 GAPDH GCC1 GIGYF1 GRN HGS HINFP HNRNPF HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP12-2 KRTAP15-1 KRTAP19-2 KRTAP19-5 KRTAP4-12 KRTAP6-2 KRTAP9-3 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 OLIG3 P4HA3 PCSK5 PDCD6IP PFKL PIN1 PITX1 PITX2 PLSCR1 PPP1R32 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBM14 RBM4B RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SH3RF1 SHANK3 SIAH1 SIAH2 SLC25A48 SLIT1 SPAG5 SS18L1 SSPOP STXBP4 SYVN1 TEKT3 TEP1 TLE1 TLE5 TNFAIP8 TRIP6 TSC1 USP2 USP54 VIM WDR5 WWP1 WWP2 ZMYND8 ZNF503 ZSWIM8	16 interacting genes: ATN1 CACNA1A CAD FBN1 FBN2 FN1 FOXN2 HOXA1 HTRA1 IGFBP3 IGFBP5 ITGB5 NOTCH3 TGFB1 TGM2 ZFP36L2
Entrez ID		1822	4052
HPRD ID		06311	01039
Ensembl ID		ENSG00000111676	ENSG00000049323
Uniprot IDs		P54259 Q86V38	B7ZLY3 Q14766
PDB IDs			1KSQ
Enriched GO Terms of Interacting Partners?
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