DNMT3A and CBX1

  • Number of citations of the paper that reports this interaction (PubMedID 12711675)
  • 247
  • Data Source:
  • HPRD (in vivo, in vitro)

DNMT3A

CBX1

Description DNA methyltransferase 3 alpha chromobox 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Body mass index ( 26426971)
  • Body mass index (age <50) ( 26426971)
  • Body mass index (age>50) ( 26426971)
  • Body mass index x sex x age interaction (4df test) ( 26426971)
  • Body shape index ( 34021172)
  • Body size at age 10 ( 32376654)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908 21102463)
  • Heel bone mineral density ( 30598549)
  • Height ( 28552196 25282103 25429064 31562340 18391951)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Hip circumference adjusted for BMI ( 34021172)
  • Hip index ( 34021172)
  • Inflammatory bowel disease ( 28067908)
  • Lymphocyte counts ( 32888494 27863252)
  • Lymphocyte percentage of white cells ( 32888494 27863252)
  • Macular thickness ( 30535121)
  • Multiple sclerosis ( 31604244)
  • Neutrophil percentage of white cells ( 32888494 27863252)
  • Resistant hypertension ( 31545351)
  • Type 1 diabetes ( 21980299)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for BMI in smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 34021172 25673412 28448500)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes 33 interacting genes: ALK CBX1 DDB1 DNMT1 DNMT3B DNMT3L EED EHMT1 EHMT2 EZH2 F8A1 H3C6 HDAC1 MDFI MEOX2 MYC NRIP1 PIAS1 PIAS2 PRMT5 PTGES3 SETDB1 SP100 SPI1 SUV39H1 TCL1A TERF2IP UBE2I UHRF1 USP7 ZBTB17 ZBTB18 ZNF513 37 interacting genes: ABI3BP ARL5A ATXN7L2 BAHD1 BARD1 BRCA1 CBX3 CBX5 CHAF1A DCAF7 DNMT1 DNMT3A DNMT3B EMSY H1-4 H3-4 H3C1 H3C3 HECW2 HSPB1 KLF11 LNX1 LRIF1 NR2F6 PCNA PIM1 RB1 RPL12 SP100 SUV39H1 TBKBP1 TRIM24 TRIM28 UCHL1 VHL VTN ZNF280C
Entrez ID 1788 10951
HPRD ID 04141 05149
Ensembl ID ENSG00000119772 ENSG00000108468
Uniprot IDs A0A0C4DG02 F8WE91 Q59HC6 Q9Y6K1 P83916 Q6IBN6
PDB IDs 2QRV 3A1A 3A1B 3LLR 3SVM 4QBQ 4QBR 4QBS 4U7P 4U7T 5YX2 6BRR 6F57 6PA7 6W89 6W8B 6W8D 6W8J 2FMM 3F2U 3Q6S 5T1G 6D07 6D08
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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