DLX2 and MVP

Number of citations of the paper that reports this interaction (PubMedID 24722188)
63

Data Source:
BioGRID (two hybrid)

		DLX2	MVP
Description		distal-less homeobox 2	major vault protein
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Extracellular Region Nucleus Nuclear Pore Cytoplasm Cytosol Cytoskeleton Membrane Secretory Granule Lumen Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Single-stranded RNA Binding Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Protein Kinase Binding Protein Phosphatase Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Brain Development Embryo Development Proximal/distal Pattern Formation Subpallium Development Hippocampus Development Olfactory Bulb Development Forebrain Neuron Differentiation Cerebral Cortex GABAergic Interneuron Fate Commitment Cell Differentiation Odontogenesis Of Dentin-containing Tooth Positive Regulation Of Cell Differentiation Negative Regulation Of Notch Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Photoreceptor Cell Differentiation Embryonic Cranial Skeleton Morphogenesis Negative Regulation Of Oligodendrocyte Differentiation Branching Morphogenesis Of A Nerve Cartilage Development Positive Regulation Of Amacrine Cell Differentiation	Protein Transport Negative Regulation Of Protein Autophosphorylation ERBB Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway MRNA Transport Negative Regulation Of Protein Tyrosine Kinase Activity
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Breast cancer ( 23535729) Food allergy ( 29030101) Peanut allergy ( 29030101)	Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		14 interacting genes: AVP DGCR6 DIP2A DLX5 GRN HOXC8 MSX1 MSX2 MVP NCOA2 PIK3R1 PRKN TSPOAP1 XRCC6	68 interacting genes: ADAMTSL4 BANP C1orf94 CALCOCO2 CAMK2B CKAP4 DISC1 DLX2 DNAH5 DTX2 EPHX2 ESR1 FMR1 FNDC3B FXR1 FXR2 GIT2 GOLGA2 HP IHO1 KCTD9 KPNA2 KPNA3 MDFI MEOX1 MEOX2 MID2 MRTFA MT-CYB NNT NOTCH2NLA NRF1 NTAQ1 PARP4 PIH1D2 PLSCR1 POT1 PSTPIP1 PTEN PTPN11 RAB3IP RBPMS REL RHOXF2 RIMBP3 RNF111 SAXO1 SERTAD1 SKIL SLC2A4 STN1 TCF4 TENT5C TFCP2 TLE5 TOLLIP TP53 TRAF2 TRIM27 TRIM42 TRIP13 TRIP6 TSPOAP1 UBC UBTD2 VAC14 ZBTB32 ZMIZ2
Entrez ID		1746	9961
HPRD ID		00527	05475
Ensembl ID		ENSG00000115844	ENSG00000013364
Uniprot IDs		Q07687 Q53QU7 X5D7D8	Q14764 X5D2M8 X5D7K9 X5DNU0
PDB IDs			1Y7X
Enriched GO Terms of Interacting Partners?
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