PSORS1C2 and MYL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PSORS1C2	MYL2
Description		psoriasis susceptibility 1 candidate 2	myosin light chain 2
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Extracellular Region	Cytosol Cytoskeleton Actin Cytoskeleton Myosin Complex Myofibril Sarcomere A Band Cardiac Myofibril
	Molecular Function	Molecular_function Protein Binding	Actin Monomer Binding Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Myosin Heavy Chain Binding
	Biological Process	Biological_process	Regulation Of The Force Of Heart Contraction Regulation Of Striated Muscle Contraction Heart Development Negative Regulation Of Cell Growth Cardiac Myofibril Assembly Ventricular Cardiac Muscle Tissue Morphogenesis Heart Contraction Positive Regulation Of The Force Of Heart Contraction
Pathways			Striated Muscle Contraction
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Broad depression or schizophrenia ( 30626913) Clostridioides difficle infection in antibiotics-users ( 33841421) Height ( 28552196 25282103) Hematology traits ( 23263863) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Metabolite levels ( 23823483) Multiple myeloma ( 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Night sleep phenotypes ( 27126917) Serum uric acid levels ( 30993211) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White blood cell count ( 21738480)	Alcohol consumption ( 21270382) Alcohol consumption (drinkers vs non-drinkers) ( 28485404) Alcohol consumption (max-drinks) ( 29460428) Body mass index ( 24861553) Coffee consumption ( 29367735) Coronary heart disease ( 23364394) Drinking behavior ( 23364009) Gamma glutamyl transpeptidase ( 21909109) Glycemic traits ( 23575436) Gout ( 25646370) HDL cholesterol ( 21909109) HDL cholesterol levels ( 28334899) High density lipoprotein cholesterol levels ( 30718733) Hypertension ( 32709000) Metabolic syndrome ( 25705158) Metabolic syndrome (multivariate analysis) ( 29632305) Neutrophil count ( 29403010) Serum uric acid levels ( 32514006) Urate levels ( 31578528) White blood cell count ( 29403010)
Interacting Genes		27 interacting genes: AGR2 AP1B1 AP2B1 BANP CEP70 ERICH2 EVPL GUCA1C HMG20A HOMER3 LHX3 MED20 MEIS3 MYL2 MYL7 NCKIPSD PAX6 PEX19 REL RTRAF SERTAD1 SGTA SGTB TTC23 UBQLN1 UBQLN2 VASP	12 interacting genes: CDC42BPA GJB5 LRSAM1 MYOC NHP2 PAK2 PKM PPP1R12C PSORS1C2 TRIM63 USP6 ZNF529
Entrez ID		170680	4633
HPRD ID		17921	01181
Ensembl ID		ENSG00000204538	ENSG00000111245
Uniprot IDs		A0A1U9X9A6 Q9UIG4	P10916 Q6IB42
PDB IDs			5TBY
Enriched GO Terms of Interacting Partners?
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