SLC30A8 and FAM210B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC30A8	FAM210B
Description		solute carrier family 30 member 8	family with sequence similarity 210 member B
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Integral Component Of Membrane Secretory Granule Transport Vesicle Membrane Secretory Granule Membrane Cytoplasmic Vesicle	Mitochondrion Mitochondrial Outer Membrane Integral Component Of Membrane Intrinsic Component Of Membrane
	Molecular Function	Zinc Ion Transmembrane Transporter Activity Protein Binding Zinc Ion Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Zinc Ion Transport Cellular Zinc Ion Homeostasis Response To Glucose Response To Zinc Ion Insulin Secretion Positive Regulation Of Insulin Secretion Sequestering Of Zinc Ion Response To Interferon-gamma Glucose Homeostasis Regulation Of Vesicle-mediated Transport Regulation Of Sequestering Of Zinc Ion Response To Interleukin-1 Zinc Ion Transmembrane Transport	Erythrocyte Maturation Positive Regulation Of Erythrocyte Differentiation Cellular Response To Estradiol Stimulus
Pathways		Insulin processing Zinc efflux and compartmentalization by the SLC30 family
Drugs
Diseases
GWAS		Asthma ( 21814517) Blood sugar levels ( 29403010) Body mass index ( 28892062) Fasting blood glucose ( 33842983 25631608 20081858 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Fasting blood glucose adjusted for BMI ( 25625282) Fasting blood proinsulin levels ( 23263489) Fasting glucose ( 33402679 34059833) Fasting plasma glucose ( 25187374 28270201) Glycated hemoglobin levels ( 24647736 34059833 19096518 28898252) Glycemic traits (pleiotropy) ( 31021400) Hemoglobin A1c levels ( 29403010) Insulin-related traits (multivariate analysis) ( 32002517) Intraocular pressure ( 24002674) Left superior temporal gyrus thickness (schizophrenia interaction) ( 26249676) Lung cancer ( 27393504) Medication use (drugs used in diabetes) ( 31015401) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Proinsulin levels ( 21873549) Triglyceride levels ( 32203549) Triglycerides ( 30275531) Type 2 diabetes ( 27189021 22885922 24509480 17293876 30054458 22693455 26961502 29358691 30297969 19734900 29632382 26818947 31217584 23945395 31118516 32499647 20581827 19401414 17463246 30718926 17463248 17463249 28869590 17460697 19056611) Type 2 diabetes (adjusted for BMI) ( 29632382) Vestibular neuritis ( 30079052)
Interacting Genes		70 interacting genes: ANK1 AQP6 ARL8B ATP13A1 BCL2L13 BSND CCL4 CD99L2 CGRRF1 CMTM7 CPLX4 CREB3L1 DERL1 ELOVL4 ERVFRD-1 FAM209A FAM210B FAXDC2 FCER1G GPR37L1 GPR42 GRM2 HMOX2 HSD17B11 JSRP1 LEUTX LMNA MUC1 NKG7 ORMDL1 OTULINL PCNA PGRMC2 PKMYT1 PLN PSCA PTPN9 REEP4 REEP6 RELL2 RMDN3 RTN3 RUSF1 SCN3B SELENOK SFT2D1 SFT2D2 SLC18A1 SLC30A3 SLC39A2 SYS1 SYT2 THAP4 THSD7B TMEM11 TMEM139 TMEM14B TMEM208 TMEM237 TMEM31 TMEM50A TMEM52B TMEM80 TMEM9 TSPAN2 VAMP1 VAMP2 YIPF4 YIPF6 ZFYVE27	62 interacting genes: ATP6V0B ATP6V0C BCL2L13 BET1 C1GALT1 C5orf46 CCDC167 CD300C CLDND2 CNIH3 CYB5B CYB5R3 CYP4F2 EMP3 FIS1 FXYD6-FXYD2 GIMAP5 HEXB HMOX1 HMOX2 IER3IP1 IFITM3 LNPEP LPAR3 MFF MS4A13 NINJ2 NKG7 ORMDL2 OTOP3 PLP2 PLPP6 RPRM RTP2 SERP1 SERP2 SLC16A13 SLC30A8 SLC35B4 SLC35G1 SMCO4 SMIM1 STX6 STX7 SYNJ2BP TF TFRC TIMM23 TIMMDC1 TMEM107 TMEM11 TMEM140 TMEM187 TMEM19 TMIE UBE2J1 VAMP1 VAMP3 VAMP4 VKORC1 YIF1A ZDHHC21
Entrez ID		169026	116151
HPRD ID		15370	12737
Ensembl ID		ENSG00000164756	ENSG00000124098
Uniprot IDs		Q8IWU4	Q96KR6
PDB IDs		6XPD 6XPE 6XPF
Enriched GO Terms of Interacting Partners?
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