DDX5 and SLC26A4-AS1

Number of citations of the paper that reports this interaction (PubMedID 32939012)
3

Data Source:
BioGRID (unspecified method, affinity chromatography technology)

		DDX5	SLC26A4-AS1
Description		DEAD-box helicase 5	SLC26A4 antisense RNA 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Extracellular Exosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	RNA Binding RNA Helicase Activity MRNA 3'-UTR Binding Protein Binding Calmodulin Binding ATP Binding ATP Hydrolysis Activity Enzyme Binding MH2 Domain Binding Pre-mRNA Binding Ribonucleoprotein Complex Binding SMAD Binding Calcium-dependent Protein Binding Androgen Receptor Binding R-SMAD Binding Primary MiRNA Binding Promoter-specific Chromatin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Nuclear-transcribed MRNA Catabolic Process Epithelial To Mesenchymal Transition Regulation Of Transcription By RNA Polymerase II MRNA Transcription BMP Signaling Pathway Intracellular Estrogen Receptor Signaling Pathway Androgen Receptor Signaling Pathway Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Viral Genome Replication Myoblast Differentiation Regulation Of Osteoblast Differentiation Rhythmic Process Regulation Of Androgen Receptor Signaling Pathway Pri-miRNA Transcription By RNA Polymerase II Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Pri-miRNA Transcription By RNA Polymerase II Positive Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA Regulation Of Skeletal Muscle Cell Differentiation
Pathways		SUMOylation of transcription cofactors mRNA Splicing - Major Pathway Estrogen-dependent gene expression Replication of the SARS-CoV-1 genome Replication of the SARS-CoV-2 genome
Drugs		Artenimol
Diseases
GWAS		Lung function (FVC) ( 30804560) Refractive error ( 32231278)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		40 interacting genes: AKAP8 CALM1 CASP8 CREBBP DDX17 DHX9 DUX4 EP300 ESR1 FBL FRS3 HNRNPA0 HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK IL7R KHDRBS1 MAPKAPK2 NCOA1 NCOA2 NCOA3 NDRG1 OGT PIAS1 PIK3CA PIN1 PRKCA PSMA3 RBFOX2 RBM10 RBM4 SLC26A4-AS1 SMAD3 SP1 SUMO2 TNNT1 TP53 UBE2I WBP11	19 interacting genes: ANXA2 CSTA DDX5 EEF1D EZR GLS2 GOLGA6L2 HP1BP3 HSPB1 LMNA LORICRIN MRC2 RPL22 RPS25 SERPINB3 TCP1 TRIM25 YBX3 ZNF326
Entrez ID		1655	286002
HPRD ID		01615
Ensembl ID		ENSG00000108654
Uniprot IDs		J3KTA4 P17844
PDB IDs		3FE2 4A4D
Enriched GO Terms of Interacting Partners?
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