DDB2 and PAQR3

Number of citations of the paper that reports this interaction (PubMedID 26205499)
10

Data Source:
BioGRID (pull down)

		DDB2	PAQR3
Description		damage specific DNA binding protein 2	progestin and adipoQ receptor family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cell Junction Cul4B-RING E3 Ubiquitin Ligase Complex Protein-containing Complex Cul4-RING E3 Ubiquitin Ligase Complex	Golgi Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	DNA Binding Damaged DNA Binding Ubiquitin-protein Transferase Activity Protein Binding Protein-containing Complex Binding	Protein Binding Signaling Receptor Activity
	Biological Process	Protein Polyubiquitination DNA Repair Nucleotide-excision Repair Pyrimidine Dimer Repair Response To UV Histone H2A Monoubiquitination Protein Autoubiquitination UV-damage Excision Repair	Negative Regulation Of Protein Phosphorylation Negative Regulation Of Neuron Projection Development Negative Regulation Of Peptidyl-serine Phosphorylation Protein Localization To Golgi Apparatus Negative Regulation Of MAP Kinase Activity
Pathways		Ub-specific processing proteases DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER Dual Incision in GG-NER TP53 Regulates Transcription of DNA Repair Genes Neddylation	Negative regulation of MAPK pathway
Drugs
Diseases
GWAS		Acne (severe) ( 24399259) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Feeling lonely ( 29500382) Feeling miserable ( 29500382) High density lipoprotein cholesterol levels ( 33339817) Lymphocyte percentage of white cells ( 32888494) Monocyte percentage of white cells ( 32888494) Neurociticism ( 29500382) Neuroticism ( 29255261) Refractive error ( 32231278) Triglyceride levels ( 32203549)	Chronotype ( 30696823) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Parkinson's disease ( 26227905)
Interacting Genes		20 interacting genes: ABL1 AR CUL4A CUL4B DCLRE1C DDB1 E2F1 H2AC20 H3C14 HDAC1 NR5A2 NTMT1 PAQR3 RAD51 SIRT6 TOP1 USP24 USP40 XPA XPC	5 interacting genes: BTRC DDB2 FRAS1 PPARA RAD23B
Entrez ID		1643	152559
HPRD ID		02886	17819
Ensembl ID		ENSG00000134574	ENSG00000163291
Uniprot IDs		Q92466	Q6TCH7
PDB IDs		3EI4 3I7L 4E54 4E5Z 6R8Y 6R8Z 6R90 6R91 6R92
Enriched GO Terms of Interacting Partners?
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