AP1G1 and AP1S1

Number of citations of the paper that reports this interaction (PubMedID 26344197)
178

Data Source:
BioGRID (biochemical, affinity chromatography technology)
HPRD (two hybrid)

		AP1G1	AP1S1
Description		adaptor related protein complex 1 subunit gamma 1	adaptor related protein complex 1 subunit sigma 1
Image
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Cytosol Membrane AP-1 Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome	Golgi Membrane Lysosomal Membrane Golgi Apparatus Cytosol Clathrin-coated Pit Membrane AP-1 Adaptor Complex Cytoplasmic Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Kinesin Binding GTP-dependent Protein Binding Small GTPase Binding Clathrin Adaptor Activity Cargo Adaptor Activity	Clathrin Adaptor Activity
	Biological Process	Intracellular Protein Transport Golgi To Vacuole Transport Receptor-mediated Endocytosis Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Golgi To Lysosome Transport	Intracellular Protein Transport Receptor-mediated Endocytosis Response To Virus Vesicle-mediated Transport
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) HDL cholesterol levels ( 32203549) Post bronchodilator FEV1 ( 26634245) Refractive error ( 32231278) Superior temporal sulcus banks volume ( 31530798)	Adult body size ( 32376654) Serum metabolite concentrations in chronic kidney disease ( 33838163)
Interacting Genes		28 interacting genes: AAGAB AFTPH AP1AR AP1B1 AP1M2 AP1S1 AP1S2 ARF1 ARFRP1 BAALC CCDC91 CLINT1 CLTC DNER EPS15 HEATR5B KIF13A MAP1A PSEN2 RABEP1 RABGEF1 SNX9 SPTB SYNRG SYP UBL7 UPF1 ZNF512B	7 interacting genes: AP1G1 AP1G2 AP1M2 AP2A2 PICK1 RHOU TNFRSF9
Entrez ID		164	1174
HPRD ID		04637	04635
Ensembl ID		ENSG00000166747	ENSG00000106367
Uniprot IDs		A0A140VJE7 O43747 Q8IY97	A0A024QYT6 P61966
PDB IDs		1IU1	4P6Z
Enriched GO Terms of Interacting Partners?
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