SASS6 and FBXW5

Number of citations of the paper that reports this interaction (PubMedID 21725316)
71

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, enzymatic study)

		SASS6	FBXW5
Description		SAS-6 centriolar assembly protein	F-box and WD repeat domain containing 5
Image			No pdb structure
GO Annotations	Cellular Component	Centrosome Centriole Cytosol Centriolar Satellite Deuterosome	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Protein Binding	Protein Binding Protein Kinase Binding
	Biological Process	Centriole Replication Centrosome Duplication	Regulation Of Mitotic Nuclear Division Regulation Of Centrosome Duplication Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways			Association of TriC/CCT with target proteins during biosynthesis Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Adiponectin levels ( 33562295)	Blood protein levels ( 29875488) Heel bone mineral density ( 30598549) Keratoconus ( 33649486) Plateletcrit ( 32888494)
Interacting Genes		3 interacting genes: FBXW5 FCHSD2 FZR1	36 interacting genes: ADAMTSL4 CYP1A1 CYSRT1 EFEMP2 FAM168A FBLN2 KRT31 KRT34 KRT37 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-1 KRTAP4-12 KRTAP6-3 KRTAP9-3 KRTAP9-4 MDFI MID2 MTUS2 MYB NBPF19 NLK NOTCH2NLA PLEKHF2 S100B SASS6 SEC23B SKP1 TRIM27 TSC2 UBE2R2 VWC2
Entrez ID		163786	54461
HPRD ID		10907	10955
Ensembl ID		ENSG00000156876	ENSG00000159069
Uniprot IDs		B4DYM7 Q495U0 Q6UVJ0	A0A024R8H7 Q969U6
PDB IDs		6Z4A
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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