DGKA and SREK1

Number of citations of the paper that reports this interaction (PubMedID 14559993)
15

Data Source:
HPRD (two hybrid)

		DGKA	SREK1
Description		diacylglycerol kinase alpha	splicing regulatory glutamic acid and lysine rich protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane	Nucleoplasm Spliceosomal Complex Nuclear Speck
	Molecular Function	NAD+ Kinase Activity Diacylglycerol Kinase Activity Calcium Ion Binding ATP Binding Lipid Binding Kinase Activity	RNA Binding Protein Binding
	Biological Process	Phosphatidic Acid Biosynthetic Process Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Platelet Activation Intracellular Signal Transduction Diacylglycerol Metabolic Process Glycerolipid Metabolic Process Lipid Phosphorylation	MRNA Processing RNA Splicing
Pathways		Effects of PIP2 hydrolysis
Drugs		Vitamin E alpha-Tocopherol succinate
Diseases
GWAS		Anorexia nervosa ( 28494655) Refractive error ( 32231278) Vitiligo ( 22951725)	Logical memory (delayed recall) in mild cognitive impairment ( 29274321) Systolic blood pressure ( 30224653)
Interacting Genes		3 interacting genes: IL21 SRC SREK1	60 interacting genes: ARL6IP4 CD8A CSNK2A1 DDX17 DDX39B DDX3X DGKA DGKD EFTUD2 ELAVL1 GPRASP2 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPH1 HNRNPK HNRNPU ILF2 MDM2 NCL NPM1 PABPC1 PABPC4 PARP1 PIN1 PRPF40A RACK1 RBM10 RBM39 RBMX SAFB SF3A3 SF3B3 SFPQ SH3GLB2 SNRPD1 SNRPD3 SRPK1 SRPK2 SRPK3 SRSF1 SRSF10 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SSRP1 SUPT16H TARBP1 THRAP3 TRA2B TXLNA YBX1 ZRANB2
Entrez ID		1606	140890
HPRD ID		00517	18043
Ensembl ID		ENSG00000065357	ENSG00000153914
Uniprot IDs		A0A024RB23 P23743	Q8WXA9
PDB IDs		1TUZ 6IIE
Enriched GO Terms of Interacting Partners?
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