NKX2-3 and GTF2A1L

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		NKX2-3	GTF2A1L
Description		NK2 homeobox 3	general transcription factor IIA subunit 1 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Cellular_component Nucleus	Transcription Factor TFIIA Complex Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding	DNA Binding Transcription Coactivator Activity Protein Binding
	Biological Process	Leukocyte Homeostasis Plasma Cell Differentiation Regulation Of Transcription By RNA Polymerase II Triglyceride Metabolic Process Biological_process Gland Morphogenesis Cell Differentiation Macrophage Differentiation Regulation Of Cell Population Proliferation Odontogenesis Of Dentin-containing Tooth CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Lymph Node Development Spleen Development Peyer's Patch Development Post-embryonic Digestive Tract Morphogenesis Leukocyte Migration	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Cognition
Pathways
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 23749187) Autoimmune thyroid disease ( 32581359) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Colorectal cancer ( 25990418 30529582 24737748) Colorectal cancer or advanced adenoma ( 30510241) Crohn's disease ( 18587394 25489960 28067908 17554261 22412388 17554300 21102463) Dental caries ( 23064961) Granulocyte percentage of myeloid white cells ( 27863252) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Hypothyroidism ( 27182965) Inflammatory bowel disease ( 28067908 23128233) Leukocyte telomere length ( 31171785) Mean corpuscular hemoglobin ( 27863252) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Pediatric autoimmune diseases ( 26301688) Red blood cell traits ( 23222517) Ulcerative colitis ( 28067908 20228798 20228799)	Adult body size ( 32376654) Hepcidin/ferritin ratio ( 27846281) Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597) Joint mobility (Beighton score) ( 27182965) Laterality in neovascular age-related macular degeneration ( 28775256) Polycystic ovary syndrome ( 21151128)
Interacting Genes		3 interacting genes: GTF2A1L SRF ZNF212	25 interacting genes: ASCL3 ATF4 CEBPE CSNK2A1 CSNK2A2 EMX1 EMX2 GAB1 GTF2A2 HMG20A HOXA5 HOXC11 HOXC9 ID3 MAFF MAFG NKX2-3 PAX9 RBFOX2 SIX6 SUB1 TBP TLX2 TLX3 ZBTB3
Entrez ID		159296	11036
HPRD ID		05992	05640
Ensembl ID		ENSG00000119919	ENSG00000242441
Uniprot IDs		Q8TAU0	A0A140VKA3 Q9UNN4
PDB IDs
Enriched GO Terms of Interacting Partners?
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